Results 1 to 10 of about 1,703,637 (357)

Monocyte/high-density lipoprotein cholesterol, neutrophil/high-density lipoprotein cholesterol, and lymphocyte/high-density lipoprotein cholesterol ratios as new inflammatory markers in rosacea

Turkderm Turkish Archives of Dermatology and Venereology, 2023
Background and Design: Rosacea is a chronic inflammatory skin disease. The monocyte/high-density lipoprotein (HDL) cholesterol ratio (MHR), neutrophil/HDL cholesterol ratio (NHR), and lymphocyte/HDL cholesterol ratio (LHR) are new inflammatory parameters
Bülent Nuri Kalaycı
doaj   +1 more source

Dysfunctional high-density lipoprotein [PDF]

Current Opinion in Endocrinology, Diabetes & Obesity, 2009
To address the progress of the investigation on dysfunctional high-density lipoprotein (HDL).HDL is generally considered to be an independent protective factor against cardiovascular disease. However, emerging evidence indicates that HDL can be modified under certain circumstances and lose its protective effect or even become atherogenic.
Hong, Feng, Xiang-An, Li
openaire   +2 more sources

Obesity-Related Changes in High-Density Lipoprotein Metabolism and Function

International Journal of Molecular Sciences, 2020
In obese individuals, atherogenic dyslipidemia is a very common and important factor in the increased risk of cardiovascular disease. Adiposity-associated dyslipidemia is characterized by low high-density lipoprotein cholesterol (HDL-C) levels and an ...
Julia T. Stadler, G. Marsche
semanticscholar   +1 more source

SR-BI-mediated selective lipid uptake segregates apoA-I and apoA-II catabolism

Journal of Lipid Research, 2005
The HDL receptor scavenger receptor class B type I (SR-BI) binds HDL and mediates the selective uptake of cholesteryl ester. We previously showed that remnants, produced when human HDL2 is catabolized in mice overexpressing SR-BI, become incrementally ...
Maria C. de Beer, Deneys van der Westhuyzen, Nathan L. Whitaker, Nancy R. Webb, Frederick C. de Beer   +4 more
doaj   +1 more source

Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis

Biomedicines, 2021
Despite advances in pharmacotherapy, intervention devices and techniques, residual cardiovascular risks still cause a large burden on public health. Whilst most guidelines encourage achieving target levels of specific lipids and lipoproteins to reduce ...
Chih-Kuo Lee, Che-Wei Liao, Shih-Wei Meng, Wei-Kai Wu, Jiun-Yang Chiang, Ming-Shiang Wu   +5 more
doaj   +1 more source

High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice1[S]

Journal of Lipid Research, 2014
The LDL receptor (LDLR) and scavenger receptor class B type I (SR-BI) play physiological roles in LDL and HDL metabolism in vivo. In this study, we explored HDL metabolism in LDLR-deficient mice in comparison with WT littermates.
Franz Rinninger, Markus Heine, Roshni Singaraja, Michael Hayden, May Brundert, Rajasekhar Ramakrishnan, Joerg Heeren   +6 more
doaj   +1 more source

Primary genetic disorders affecting high density lipoprotein (HDL)

Drugs in Context, 2018
There is extensive evidence demonstrating that there is a clear inverse correlation between plasma high density lipoprotein cholesterol (HDL-C) concentration and cardiovascular disease (CVD).
Constantine E Kosmas, Delia Silverio, Andreas Sourlas, Frank Garcia, Peter D Montan, Eliscer Guzman   +5 more
doaj   +1 more source

Coronary risk prediction by the correlation of total cholesterol/high-density lipoprotein, triglyceride/high-density lipoprotein, low-density lipoprotein/high-density lipoprotein ratios, non-high-density lipoprotein, apolipoprotein-B, and high-sensitivity C-reactive protein with low-density lipoprotein in Indian patients under statin therapy

Heart India, 2019
Background: Patients are treated with statins for the control of cholesterol; but statins control only low-density lipoprotein (LDL) and not non-high-density lipoprotein (non-HDL). Also, LDL is not a good coronary risk predictor.
A K Badrinath, K Nagarajan, P Anand, S Suresh Babu, S Asmathulla, M Mohammad Inaamul Hassan   +5 more
doaj   +1 more source

Alternations of Lipoprotein Profiles in the Plasma as Biomarkers of Huntington’s Disease

Cells, 2023
Alterations in lipid composition and disturbed lipoprotein metabolism are involved in the pathomechanism of Huntington’s disease (HD). Here, we measured 112 lipoprotein subfractions and components in the plasma of 20 normal controls, 24 symptomatic ...
Kuo-Hsuan Chang, Mei-Ling Cheng, Chi-Jen Lo, Chun-Ming Fan, Yih-Ru Wu, Chiung-Mei Chen   +5 more
doaj   +1 more source

Changes in high-density lipoprotein cholesterol with risk of Cardiovascular Disease among initially high-density lipoprotein-high participants

Cardiovascular Diabetology, 2023
Background High-density lipoprotein cholesterol’s (HDL-C) long-held status as a cardiovascular disease (CVD) preventative has been called into question. Most of the evidence, however, focused on either the risk of death from CVD, or on single time point ...
Hye Jun Kim, Seogsong Jeong, Yun Hwan Oh, Sun Jae Park, Yoosun Cho, Sang Min Park   +5 more
doaj   +1 more source