Results 41 to 50 of about 264,049 (257)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

dN/dx reconstruction with deep learning for high-granularity TPCs

Journal of High Energy Physics
Particle identification (PID) is essential for future particle physics experiments such as the Circular Electron-Positron Collider (CEPC) and the Future Circular Collider.
Guang Zhao, Yue Chang, Jinxian Zhang, Linghui Wu, Huirong Qi, Xin She, Mingyi Dong, Shengsen Sun, Jianchun Wang, Yifang Wang, Chunxu Yu   +10 more
doaj   +1 more source

HEPS scientific computing platform design for interactive data analysis scenarios [PDF]

EPJ Web of Conferences
The High Energy Photon Source (HEPS), located at Beijing HuaiRou, is an advanced public platform for multidisciplinary innovation research and high-tech development, as well as understanding many scientific questions in the fields of physics, chemistry ...
Hu Qingbao, Zheng Wei, Yan Xiaofei, Li Binbin, Cheng Yaosong, Xu Jiping   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Using Kerberos Tokens in Distributed Computing System at IHEP [PDF]

EPJ Web of Conferences
The token-based certification method is spreading in the distributed computing system of high energy physics. More and more software and middleware are supporting tokens as one of the certification methods.
Jiang Xiaowei, Guo Chaoqi, Hu Qingbao, Du Ran, Shi Jingyan, Sun Gongxing   +5 more
doaj   +1 more source

Amplitude analysis and branching fraction measurement of the decay D s + $$ {\textrm{D}}_{\textrm{s}}^{+} $$ → K+ π + π − π 0

Journal of High Energy Physics, 2022
The singly Cabibbo-suppressed decay D s + $$ {D}_s^{+} $$ → K + π + π − π 0 is observed by using a data set corresponding to an integrated luminosity of 6.32 fb −1 recorded by the BESIII detector at the centre-of-mass energies between 4.178 and 4.226 GeV.
The BESIII collaboration, M. Ablikim, M. N. Achasov, P. Adlarson, M. Albrecht, R. Aliberti, A. Amoroso, M. R. An, Q. An, X. H. Bai, Y. Bai, O. Bakina, R. Baldini Ferroli, I. Balossino, Y. Ban, V. Batozskaya, D. Becker, K. Begzsuren, N. Berger, M. Bertani, D. Bettoni, F. Bianchi, J. Bloms, A. Bortone, I. Boyko, R. A. Briere, A. Brueggemann, H. Cai, X. Cai, A. Calcaterra, G. F. Cao, N. Cao, S. A. Cetin, J. F. Chang, W. L. Chang, G. Chelkov, C. Chen, Chao Chen, G. Chen, H. S. Chen, M. L. Chen, S. J. Chen, S. M. Chen, T. Chen, X. R. Chen, X. T. Chen, Y. B. Chen, Z. J. Chen, W. S. Cheng, X. Chu, G. Cibinetto, F. Cossio, J. J. Cui, H. L. Dai, J. P. Dai, A. Dbeyssi, R. E. de Boer, D. Dedovich, Z. Y. Deng, A. Denig, I. Denysenko, M. Destefanis, F. De Mori, Y. Ding, J. Dong, L. Y. Dong, M. Y. Dong, X. Dong, S. X. Du, P. Egorov, Y. L. Fan, J. Fang, S. S. Fang, W. X. Fang, Y. Fang, R. Farinelli, L. Fava, F. Feldbauer, G. Felici, C. Q. Feng, J. H. Feng, K. Fischer, M. Fritsch, C. Fritzsch, C. D. Fu, H. Gao, Y. N. Gao, Yang Gao, S. Garbolino, I. Garzia, P. T. Ge, Z. W. Ge, C. Geng, E. M. Gersabeck, A. Gilman, K. Goetzen, L. Gong, W. X. Gong, W. Gradl, M. Greco, L. M. Gu, M. H. Gu, Y. T. Gu, C. Y Guan, A. Q. Guo, L. B. Guo, R. P. Guo, Y. P. Guo, A. Guskov, T. T. Han, W. Y. Han, X. Q. Hao, F. A. Harris, K. K. He, K. L. He, F. H. Heinsius, C. H. Heinz, Y. K. Heng, C. Herold, M. Himmelreich, G. Y. Hou, Y. R. Hou, Z. L. Hou, H. M. Hu, J. F. Hu, T. Hu, Y. Hu, G. S. Huang, K. X. Huang, L. Q. Huang, L. Q. Huang, X. T. Huang, Y. P. Huang, T. Hussain, N. Hüsken, W. Imoehl, M. Irshad, J. Jackson, S. Jaeger, S. Janchiv, Q. Ji, Q. P. Ji, X. B. Ji, X. L. Ji, Y. Y. Ji, Z. K. Jia, H. B. Jiang, S. S. Jiang, X. S. Jiang, Y. Jiang, J. B. Jiao, Z. Jiao, S. Jin, Y. Jin, M. Q. Jing, T. Johansson, N. Kalantar-Nayestanaki, X. S. Kang, R. Kappert, M. Kavatsyuk, B. C. Ke, I. K. Keshk, A. Khoukaz, P. Kiese, R. Kiuchi, R. Kliemt, L. Koch, O. B. Kolcu, B. Kopf, M. Kuemmel, M. Kuessner, A. Kupsc, W. Kühn, J. J. Lane, J. S. Lange, P. Larin, A. Lavania, L. Lavezzi, Z. H. Lei, H. Leithoff, M. Lellmann, T. Lenz, C. Li, C. Li, C. H. Li, Cheng Li, D. M. Li, F. Li, G. Li, H. Li, H. B. Li, H. J. Li, H. N. Li, J. Q. Li, J. S. Li, J. W. Li, Ke Li, L. J Li, L. K. Li, Lei Li, M. H. Li, P. R. Li, S. X. Li, S. Y. Li, T. Li, W. D. Li, W. G. Li, X. H. Li, X. L. Li, Xiaoyu Li, Z. Y. Li, H. Liang, H. Liang, H. Liang, Y. F. Liang, Y. T. Liang, G. R. Liao, L. Z. Liao, J. Libby, A. Limphirat, D. X. Lin, T. Lin, B. J. Liu, C. X. Liu, D. Liu, F. H. Liu, Fang Liu, Feng Liu, G. M. Liu, H. Liu, H. B. Liu, H. M. Liu, Huanhuan Liu, Huihui Liu, J. B. Liu, J. L. Liu, J. Y. Liu, K. Liu, K. Y. Liu, Ke Liu, L. Liu, Lu Liu, M. H. Liu, P. L. Liu, Q. Liu, S. B. Liu, T. Liu, W. K. Liu, W. M. Liu, X. Liu, Y. Liu, Y. B. Liu, Z. A. Liu, Z. Q. Liu, X. C. Lou, F. X. Lu, H. J. Lu, J. G. Lu, X. L. Lu, Y. Lu, Y. P. Lu, Z. H. Lu, C. L. Luo, M. X. Luo, T. Luo, X. L. Luo, X. R. Lyu, Y. F. Lyu, F. C. Ma, H. L. Ma, L. L. Ma, M. M. Ma, Q. M. Ma, R. Q. Ma, R. T. Ma, X. Y. Ma, Y. Ma, F. E. Maas, M. Maggiora, S. Maldaner, S. Malde, Q. A. Malik, A. Mangoni, Y. J. Mao, Z. P. Mao, S. Marcello, Z. X. Meng, J. G. Messchendorp, G. Mezzadri, H. Miao, T. J. Min, R. E. Mitchell, X. H. Mo, N. Yu. Muchnoi, Y. Nefedov, F. Nerling, I. B. Nikolaev, Z. Ning, S. Nisar, Y. Niu, S. L. Olsen, Q. Ouyang, S. Pacetti, X. Pan, Y. Pan, A. Pathak, M. Pelizaeus, H. P. Peng, K. Peters, J. L. Ping, R. G. Ping, S. Plura, S. Pogodin, V. Prasad, F. Z. Qi, H. Qi, H. R. Qi, M. Qi, T. Y. Qi, S. Qian, W. B. Qian, Z. Qian, C. F. Qiao, J. J. Qin, L. Q. Qin, X. P. Qin, X. S. Qin, Z. H. Qin, J. F. Qiu, S. Q. Qu, K. H. Rashid, C. F. Redmer, K. J. Ren, A. Rivetti, V. Rodin, M. Rolo, G. Rong, Ch. Rosner, S. N. Ruan, A. Sarantsev, Y. Schelhaas, C. Schnier, K. Schoenning, M. Scodeggio, K. Y. Shan, W. Shan, X. Y. Shan, J. F. Shangguan, L. G. Shao, M. Shao, C. P. Shen, H. F. Shen, X. Y. Shen, B. A. Shi, H. C. Shi, J. Y. Shi, Q. Q. Shi, R. S. Shi, X. Shi, X. D. Shi, J. J. Song, W. M. Song, Y. X. Song, S. Sosio, S. Spataro, F. Stieler, K. X. Su, P. P. Su, Y. J. Su, G. X. Sun, H. Sun, H. K. Sun, J. F. Sun, L. Sun, S. S. Sun, T. Sun, W. Y. Sun, X. Sun, Y. J. Sun, Y. Z. Sun, Z. T. Sun, Y. H. Tan, Y. X. Tan, C. J. Tang, G. Y. Tang, J. Tang, L. Y Tao, Q. T. Tao, J. X. Teng, V. Thoren, W. H. Tian, Y. Tian, I. Uman, B. Wang, B. L. Wang, C. W. Wang, D. Y. Wang, F. Wang, H. J. Wang, H. P. Wang, K. Wang, L. L. Wang, M. Wang, Meng Wang, S. Wang, S. Wang, T. Wang, T. J. Wang, W. Wang, W. H. Wang, W. P. Wang, X. Wang, X. F. Wang, X. L. Wang, Y. Wang, Y. D. Wang, Y. F. Wang, Y. H. Wang, Y. Q. Wang, Yaqian Wang, Z. Wang, Z. Y. Wang, Ziyi Wang, D. H. Wei, F. Weidner, S. P. Wen, D. J. White, U. Wiedner, G. Wilkinson, M. Wolke, L. Wollenberg, J. F. Wu, L. H. Wu, L. J. Wu, X. Wu, X. H. Wu, Y. Wu, Y. J Wu, Z. Wu, L. Xia, T. Xiang, D. Xiao, G. Y. Xiao, H. Xiao, S. Y. Xiao, Y. L. Xiao, Z. J. Xiao, C. Xie, X. H. Xie, Y. Xie, Y. G. Xie, Y. H. Xie, Z. P. Xie, T. Y. Xing, C. F. Xu, C. J. Xu, G. F. Xu, H. Y. Xu, Q. J. Xu, X. P. Xu, Y. C. Xu, Z. P. Xu, F. Yan, L. Yan, W. B. Yan, W. C. Yan, H. J. Yang, H. L. Yang, H. X. Yang, L. Yang, S. L. Yang, Tao Yang, Y. F. Yang, Y. X. Yang, Yifan Yang, M. Ye, M. H. Ye, J. H. Yin, Z. Y. You, B. X. Yu, C. X. Yu, G. Yu, T. Yu, C. Z. Yuan, L. Yuan, S. C. Yuan, X. Q. Yuan, Y. Yuan, Z. Y. Yuan, C. X. Yue, A. A. Zafar, F. R. Zeng, X. Zeng, Y. Zeng, Y. H. Zhan, A. Q. Zhang, B. L. Zhang, B. X. Zhang, D. H. Zhang, G. Y. Zhang, H. Zhang, H. H. Zhang, H. H. Zhang, H. Y. Zhang, J. J. Zhang, J. L. Zhang, J. Q. Zhang, J. W. Zhang, J. X. Zhang, J. Y. Zhang, J. Z. Zhang, Jianyu Zhang, Jiawei Zhang, L. M. Zhang, L. Q. Zhang, Lei Zhang, P. Zhang, Q. Y. Zhang, Shuihan Zhang, Shulei Zhang, X. D. Zhang, X. M. Zhang, X. Y. Zhang, X. Y. Zhang, Y. Zhang, Y. T. Zhang, Y. H. Zhang, Yan Zhang, Yao Zhang, Z. H. Zhang, Z. Y. Zhang, Z. Y. Zhang, G. Zhao, J. Zhao, J. Y. Zhao, J. Z. Zhao, Lei Zhao, Ling Zhao, M. G. Zhao, Q. Zhao, S. J. Zhao, Y. B. Zhao, Y. X. Zhao, Z. G. Zhao, A. Zhemchugov, B. Zheng, J. P. Zheng, Y. H. Zheng, B. Zhong, C. Zhong, X. Zhong, H. Zhou, L. P. Zhou, X. Zhou, X. K. Zhou, X. R. Zhou, X. Y. Zhou, Y. Z. Zhou, J. Zhu, K. Zhu, K. J. Zhu, L. X. Zhu, S. H. Zhu, S. Q. Zhu, W. J. Zhu, Y. C. Zhu, Z. A. Zhu, B. S. Zou, J. H. Zou   +568 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source