Results 61 to 70 of about 21,600,427 (264)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

The use of computers in high energy physics experiments [PDF]

open access: yesJournal of Physics E: Scientific Instruments, 1969
An introductory description is given of the nature of high energy physics experiments and of the characteristics of the detectors employed; the main uses of computers in this field are briefly outlined. A more detailed review is made of the role of computers in film measurement and data taking methods, indicating the limitations set by present ...
D Lord, G R Macleod
openaire   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Search for new physics in events with same-sign dileptons and jets in pp collisions at ?s = 8 TeV

open access: yes, 2014
A search for new physics is performed based on events with jets and a pair of isolated, same-sign leptons. The results are obtained using a sample of proton-proton collision data collected by the CMS experiment at a centre-of-mass energy of 8 TeV at the ...
Physics Collaboration, CMS Collaboration
core   +1 more source

CALET on the ISS: a high energy astroparticle physics experiment

open access: yesJournal of Physics: Conference Series, 2016
CALET is a space mission of the Japanese Aerospace Agency (JAXA) in collaboration with the Italian Space Agency (ASI) and NASA. The CALET instrument (CALorimetric Electron Telescope) is planned for a long exposure on the JEM-EF, an external platform of the Japanese Experiment Module KIBO, aboard the International Space Station (ISS).
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Charm physics with the CHORUS experiment [PDF]

open access: yes, 2005
High energy neutrino interactions induce charmed hadron production at the level of a few percent and therefore they constitute a powerful tool to study charm physics.
De Lellis, Giovanni
core  

Search for anomalous production of prompt like-sign lepton pairs at root s=7 TeV with the ATLAS detector [PDF]

open access: yes, 2012
ATLAS Contributor: Paul Douglas Jackson of School of Chemistry and Physics, University of Adelaide, Adelaide, Australia Extent: 41p.An inclusive search for anomalous production of two prompt, isolated leptons with the same electric charge is presented ...
G. Khoriauli   +999 more
core   +4 more sources

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