Results 41 to 50 of about 943,981 (241)

Diamond detectors for high energy physics experiments [PDF]

open access: yesJournal of Instrumentation, 2018
Beam test results of the radiation tolerance study of chemical vapour deposition (CVD) diamond against different particle species and energies is presented. We also present beam test results on the independence of signal size on incident particle rate in charged particle detectors based on un-irradiated and irradiated poly-crystalline CVD diamond over ...
Bäni, L.   +129 more
openaire   +4 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Small-x Physics with the ALICE experiment at the CERN-LHC

open access: yes, 2010
High energy p-p, p-Pb and Pb-Pb collisions at the CERN-LHC offer unprecedented opportunities for studying wide variety of physics at small Bjorken-x. Here we discuss capabilities of the ALICE experiment at the CERN-LHC for probing small-x QCD physics.
Aamodt   +15 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Overview of LHCb

open access: yes, 2005
An overview of LHCb experiment is given, focusing on detector, trigger and expected physics performances. LHCb is a second generation b physics experiment design to do precise measurements of CP violation in B meson system and to study b hadron rare ...
Terrier, H.
core  

Heavy Ion physics with the ALICE experiment at the CERN LHC

open access: yes, 2011
After close to 20 years of preparation, the dedicated heavy ion experiment ALICE took first data at the CERN LHC accelerator with proton collisions at the end of 2009 and with lead nuclei at the end of 2010. After a short introduction into the physics of
Schukraft, J.
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

B Decays at BABAR

open access: yes, 2003
We present branching fraction and CP asymmetry results for a variety of B decays based on up to 56.4 fb^-1 collected by the BaBar experiment running near the Upsilon(4S) resonance at the PEP-II e+e- B-factory.Comment: 10 pages, 6 figures, presented at ...
Abe   +31 more
core   +1 more source

CALET on the ISS: a high energy astroparticle physics experiment

open access: yesJournal of Physics: Conference Series, 2016
CALET is a space mission of the Japanese Aerospace Agency (JAXA) in collaboration with the Italian Space Agency (ASI) and NASA. The CALET instrument (CALorimetric Electron Telescope) is planned for a long exposure on the JEM-EF, an external platform of the Japanese Experiment Module KIBO, aboard the International Space Station (ISS).
openaire   +1 more source

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