Results 31 to 40 of about 416,182 (263)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Training and onboarding initiatives in high energy physics experiments

Frontiers in Big Data
In this article we document the current analysis software training and onboarding activities in several High Energy Physics (HEP) experiments: ATLAS, CMS, LHCb, Belle II and DUNE. Fast and efficient onboarding of new collaboration members is increasingly important for HEP experiments.
Allison Reinsvold Hall, Nicole Skidmore, Gabriele Benelli, Ben Carlson, Ben Carlson, Claire David, Jonathan Davies, Wouter Deconinck, David DeMuth, Peter Elmer, Rocky Bala Garg, Stephan Hageböck, Killian Lieret, Valeriia Lukashenko, Valeriia Lukashenko, Sudhir Malik, Andy Morris, Heidi Schellman, Graeme A. Stewart, Jason Veatch, Michel Hernandez Villanueva   +20 more
openaire   +5 more sources

HepSim: A Repository with Predictions for High-Energy Physics Experiments [PDF]

Advances in High Energy Physics, 2015
A file repository for calculations of cross sections and kinematic distributions using Monte Carlo generators for high-energy collisions is discussed. The repository is used to facilitate effective preservation and archiving of data from theoretical calculations and for comparisons with experimental data.
openaire   +3 more sources

The Duals of Fusion Frames for Experimental Data Transmission Coding of High Energy Physics

, 2013
The experimental data transmission is an important part of high energy physics experiment. In this paper, we connect fusion frames with the experimental data transmission implement of high energy physics.
J. Leng, Qi Guo, Tingzhu Huang
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

FPGA Based Particle Identification in High Energy Physics Experiments

2012 IEEE 23rd International Conference on Application-Specific Systems, Architectures and Processors, 2012
High energy physics experiments require on-the-fly processing of signals from many particle detectors. Such signals contain a high and fluctuating rate of pulses. Pulse shape hints particle type, and the amplitude relates to energy of the particle, while pulse occurrence times are needed for event reconstruction.
H. Fatih Ugurdag, Ali Basaran, Taylan Akdogan, V. Ugur Güney, Sezer Gören 0001   +4 more
openaire   +2 more sources

GPU for triggering in High Energy Physics Experiments [PDF]

Proceedings of Technology and Instrumentation in Particle Physics 2014 — PoS(TIPP2014), 2015
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Sidoti, Antonio, Amerio, Silvia, Belgiovine, Mauro, Di Sipio, Riccardo, Gabrielli, Alessandro, Gianelle, Alessio, Lucchesi, Donatella, Negrini, Matteo, Rinaldi, Lorenzo, Semeria, Franco, Villa, Mauro   +10 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source