Results 21 to 30 of about 22,846,713 (218)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Research in High Energy Physics [PDF]

, 2013
This final report details the work done from January 2010 until April 2013 in the area of experimental and theoretical high energy particle physics and cosmology at the University of California ...
Conway, John S.
core  

Report of the Subpanel on High Energy Physics Manpower of the High Energy Physics Advisory Panel

, 1978
A report of a study by a Subpanel which was appointed by the High Energy Physics Advisory Panel (HEPAP) to examine the production in recent years of new researchers in high energy physics and the rate at which they have moved into short term and ...

core   +1 more source

Neutrino Oscillation Physics [PDF]

, 2012
To complement the neutrino-physics lectures given at the 2011 International School on Astro Particle Physics devoted to Neutrino Physics and Astrophysics (ISAPP 2011; Varenna, Italy), at the 2011 European School of High Energy Physics (ESHEP 2011; Cheila
Kayser, Boris
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Search for dark matter candidates and large extra dimensions in events with a jet and missing transverse momentum with the ATLAS detector [PDF]

, 2012
ATLAS Collaboration Contributors: Paul Douglas Jackson and Nitesh SoniA search for new phenomena in events with a high-energy jet and large missing transverse momentum is performed using data from proton-proton collisions at √s = 7 TeV with the ATLAS ...
The ATLAS collaboration, ATLAS Collaboration, Kaezmarska, A, G. Khoriauli, Alessandria, F, S. O. Holmgren, Arce ATH, Smizanska, M, Blair, R, Keung, J, Strang, M, Hasegawa, S., G. Eigen, Aguilar-Saavedra, J. A., Carminati, L., Hubaut, F., Cantero, J., M. Mazur, E. Etzion, P. Hansson, Meyer, C., Ma, Baak, Dudarev, A., Oren, Y., Skottowe, H, Borissov, G., F. Dinut, Hellman, S, Harper, D, Korn, A., Oliver García, Elena, Laplace, S., Y. Smirnov, Higón Rodríguez, Emilio, Kim, H., D. Chakraborty, Cavalli Sforza, M, Kanzaki, J, Schaefer, D., J. M. Seixas, A. Talyshev, T. Naumann, Pranko, A, Epp, B., Hawkings, R. J., Jakoubek, T, Fernando, W, Ahlen, S. P., Froeschl, R., J. Keung, G. Nunes Hanninger, Leney, K, S. AbouZeid, Joshi, K. D., J. Tojo, Dameri, M., Daya-Ishmukhametova, R, M. Villa, Abreu, H, Huettmann, A, Pizio, C., Eldik, N., A. Tonoyan, W. J. Dearnaley, Jon-And, K., B. Caron, Köneke, K., Tasevsky, M., Siragusa, G, Gregor, I. M., Salzburger, A., S. Kaneti, Vacek, V, Carlino, G., R. Kopeliansky, Torrence, E., Oliveira, M, Bogaerts, J, I. Gough Eschrich, Snyder, S, Kirk, J, Ziolkowski, M, P. Grenier, Kourkoumelis, C., Oh, S. H., V. Dao, Dai, T., Lefebvre, M, T. Mueller, M. Uslenghi, Bernat, P., G. Alexandre, I. N. Aleksandrov, Engl, A, A. Juste Rozas, Asai S, Arnault, C., Bortolotto, V, Kiryunin, A, M. Klein, Negri, G., Moreno Llácer, María, Valkar, S, D. M. Rebuzzi, T. Todorov, T. Sumida, Llácer, M. Moreno, Olszewski, A., Knue, A, M. Medinnis, L. Mijović, Harris, O, D. Turecek, Hughes, G., Cheatham, S, Joram, C, Mashimo, T, M. H. Genest, P. Stavina, Smizanska, M., R. Caftei, Nelson, T. K., Kersten, S, Donald, J. Mc, Weng, Z., Schaepe, S., Schovancova, J., M. S. Weber, Reale, V, Sircar, A., Vassilakopoulos, V, Oliveira, Miguel Alfonso, Bruneliere, R, S. Menke, Darlea, G, Y. C. Coadou, M. Agustoni, Potter, C. T., Massol, N, Benoit M, Morello, G., L. Rumyantsev, Negri, A., Kawamoto, T, K. Tackmann, Castaneda Miranda, E, Manfredini, A, J. E. García Navarro, Ji, W., Teng, P. K., Charlton, D. C., Michal, S, R. Camacho Toro, D. G. Charlton, Salihagic, D, Karnevskiy, M., Papadelis, Aras,, B. Budick, J. Zhu, Liu, C., Bronner, J., J. B. Liu, J. Toth, González de la Hoz, Santiago, Ertel, E., Cornelissen, T, Schwierz, R., J. L. Pinfold, Vincter, M. G., D’Orazio, A., Barr, A, Köpke, L., J. Griffiths, Nisati, A, Strong, J, M. F. Tripiana, Deviveiros, P, M. Werner, Marx, M, Liu, D., V. B?scher, A. F. Saavedra, A. Ludwig, V. Vrba, P. T. Keener, Selbach, K, Brendinger, K, V. Andrei, M. Wright, A. Petridis, Orr, R, Ja, Aguilar Saavedra, Carrillo Montoya GD, O. Le Dortz, Lellouch, D., G. Cataldi, Bini, C, Hedberg, V, D. A. Milstead, Ferretti, C., Kobel, M, E. Pasqualucci, Bednyakov, V, Lubatti, H, A. Polini, CAMARRI, PAOLO, Puzo, P, Nozka, L, Yu, J, R. Veness, Da Cunha Sargedas De Sousa, Mario Jose, Lancon, E, Marroquim, F, Yu, D, Z. Zhang, Abdelalim, A. A., Liss, T, Johansson, K. E., Benslama, K., Poel, E., Ellis, K, Norberg, S, Kolanoski, H., Baak, M, Muino, P, Allwood Spiers, S. E., Kowalewski, R., Sjölin, J., Bates, RL, K. Iordanidou, Wells, P. S., Oreglia, M, Parzefall, U, F. M. Newcomer, Hillier, S, T. Nattermann, Huseynov, N, N. Benekos, Medinnis, M., Charlton, D. G., Sadrozinski, H, Zhou, Y., Pauly, T, V. Kral, Lopes, Lourenco, Errede, S., Liu, H., F. Niedercorn, R. Ueno, Petrucci, F., Rijssenbeek, M., Kaci, M, Marchese, F., R. Ströhmer, Krumshteyn, Z, T. Kuhl, G. Romeo, Dwuznik, M., Smirnova, O, Doi, Y., Cooke, M., B. Vachon, Richter, R., Smirnova, L, S. Schmitt, Diehl, E, Olchevski, A. G., Oberlack, H, L. Serkin, Avolio, G, Dolgoshein, B. A., M. Garcia-Sciveres, T. M. Liss, Nikolic-Audit, I, Weng, Z, Sw. Banerjee, M. C. N. Fiolhais, Milov, A, A. J. Lowe, R. Seuster, P. Loch, E. Piccaro, Buat, Q., Donadelli, M., Taylor, F. E., S. Monzani, Blair, RE, Donadelli, M, McFarlane, K. W., Ros, E., Argyropoulos, S, Ciocca, C., Lipeles, E., R. Bartoldus, Molfetas, A., Tripiana, M. F., Bhimji W, Rybar, M, H. M. Gray, Cantrill, R, Zobernig, G., Kroha, H, Coccaro, A., B. M. A., Gössling, C., Clark PJ, Meroni, C, Tayalati, Y, Ciftci AK, Andrieux, M.-L., Branchini P, Y. Bai, Lie, K, Davygora, Y., Kawamura, G, Solovyev, V., E. Sarkisyan-Grinbaum, S. Bentvelsen, B. Martin dit Latour, Davies, M, Pommès, K., Byszewski, M, Davies, L, Andeen T, Strang, M., Klemetti, M, Jamin, D. O., Keung, J., Blumenschein U, Ippolito, V., Lantzsch, K., Sbrizzi, A., Camacho Toro, Reina Coromoto, Gray, J. A., Kuwertz, Emma,, Fournier, D., G. Otero y Garzon, Straessner, A., Y. Makida, Tylmad, M., Fiorini, L., C. Bertella, M. G. Wilson, Dudarev, A, Busato E, Schroeder, C., L. Batkova, Bittner, B., A. Dudarev, E. Ertel, Lange, C, Chafaq, A., Lantzsch, K, Grivaz, J.-F., Francavilla, P., Battistin M, Gorini, B., Wiglesworth, C., I. Bloch, Hansen, J. B., Ueda, I., P. Wienemann, Kroha, H., Beddall, A, Alhroob, M., Tsiskaridze, N, Tsiskaridze, S, S. Heisterkamp, Kurata, M, Ren, Z, Salek, D, P. Calfayan, Maettig, S, G. Anders, Bianchini, L., J. M. Izen, Fisher, M, Lobodzinska, E., CHIEFARI, GIOVANNI, H. G. Sander, Bartoldus, R., Bagnaia P, Lagouri, T, Patricelli, S., Verducci, M., J. Ebke, Milosavljevic, M. Vranjes, Wielers, M., Odaka, S, Nikolic-Audit, I., D. C. O’Neil, Walsh, B, D. S. Popovic, Hansen, J. D., Barajas, C, S. Cole, de Jong, P., Vermeulen, J. C., H. Ji, E. Vilucchi, Schorlemmer, A. L. S., J. Lorenz, P. Vankov, A. Ruschke, A. Gibson, Mechnich, J., Chislett, RT, Baranov, S, J. R. Carter, Hadavand, H. K., S. Vallecorsa, Ciftci, R., M. T. Pérez García-Estañ, M. Raymond, Angelidakis, S, X. S. Anduaga, C. Stanescu, Hajduk, Z, S. Mahmoud, Zhou, B., Schwemling, Ph., Alexandre, G, Aleksandrov IN, Burgess, T., Kado, M., Oveharova, A, Khubua, J., Spagnolo, S., Ikeno, M., M. Pohl, M. Ciubancan, Bocchetta, S, Gagnon, P., F. Hahn, Klok, P, Nakahama, Y., J. Kroseberg, J. Labbe, H. Li, Rybar, M., P. J. Clark, Popeneciu, G. A., Aharrouche, M, G. Alexander, H. Ma, Bremer, J., Cowan, G, Gadfort, T, Ekelof, T., Chromek Burckhart, D., Shupe, M, Rm, Barnett, Kluth, S., AbouZeid, S, Sipica, V., Errede, D., P. Cirkovic, Steele, G., El Moursli, RC, Levinson, L. J., Beloborodova O, Kasieezka, G, Cattai, A., O’Neil, D. C., Piec, S. M., Sartisohn, G., D’Auria, S., M. Schumacher, P. Federic, Ladygin, E., Rubinskiy, I., Fratina, S., Carrillo-Montoya, G. D., J. Meyer, Makovec, N, Lundberg, B, Kabana, S., L. A. Bella, J. Buchanan, Lundberg, J, Bruschi, M, Havward, H, A. M. Castaneda, Lundberg, O, Giorgi, F, Sauvage, G, Bednyakov, V. A., Gorini, E., Zhou, N., Poveda, J., Grosse-Knetter, J., Lundberg, Olof,, Frank, T, de la Torre, H., Azuelos, G, Cerutti, F, Schwegler, P, Petrolo, E., Murray, W. J., G. L. Darlea, R. Hauser, Bouhova-Thacker EV, Vladoiu, D, Hansen, J. R., Calvet, D., L. Fayard, Tóth, József, H. Schulz, Slater, M., Curatolo, M., Djobava, T., G. Poulard, N. Amram, V. B. Vinogradov, Hassani, S, M. Morii, Hillert, S, Wingerter-Seez, I., Krieger, N, Rossi, E., P. Gerlach, Krieger, P, D. Kar, B. Liberti, Childers, J, B. H. Smart, García García, Carmen, G. Lenzen, Keeler, R., Bawa, HS, F. Derue, M-A. Dufour, Maltezos, S., Chu, M. L., T. Djobava, Stelzer-Chilton, O., P. W. Phillips, Potter, C. J., H. G. Wilkens, Simic, L, Brelier B, Saleem, M., Anduaga XS, C. Schiavi, Dhullipudi, R., Kar, D., Subramania, H, T. Nunnemann, A. Salamon, S. Stern, Taylor, C., K. Bos, Kishimoto, T., Goddard, J. R., Mechtel, M, Henrot-Versille, S., Bardin, DY, Lehmacher, M., Kono, T, M. Caprini, J. Rothberg, Buttinger, W., T. Wenaus, Paramonov, A, Joffe, D, Farrell, S, P. K. Behera, Seliverstov, D. M., Gray, H, Ženiš, T., Gray, J, F. Quinonez, Rosenbaum, G, Blocker C, Gillberg, D, B. K. Gjelsten, D. M. Gingrich, Banas, E., Losty, M. J., Tani, K., Zhu, J., Bianchi, R. M., Esposito, B, J. Schaarschmidt, Milov, A., Beau T, Bacci, C, T. Nobe, T. Colombo, B. Guo, D. Rahm, Malecki, Pa., Grishkevich, Y. V., Tani, K, V. Martinez Outschoorn, Zhu, H., Ciocca, C, H. van der Graaf, Rl, Bates, Kortner, O., Einsweiler, K., Venturi, M., T. Kobayashi, Zajaeova, Z, Catastini, P, O. Simard, Mechnich, J, Prokoshin, F, C. P. Paleari, De Groot, N, Weigell, P, M. Aurousseau, Burckhart, H., H. K. Hadavand, Prasad, S., A. Lucotte, A. Zibell, Plamondon, M, X. Wu, B. Alvarez Gonzalez, Royon, C, J. Ferencei, Vartapetian, A, Derkaoui, J. E., Buckley, AG, H. Okawa, Ohm, C. C., Uchida, K., R. Keeler, Ae, Barton, S. B. Harpaz, Cantrill, R., A. M. Castaneda Hernandez, Abdallah J, P. Dervan, Labarga, L., Blazek, T., Harkusha, S., Meoni, E., Koutsman, A, Harvey, A., P. Koevesarki, Dube, S., D. Levin, P. Schacht, Kitamura, T., Caloba, L, Kogan, L, Clarke, R. N., Tassi, E, Bertin A, Calderini G, Pasqualucci, E., Simoniello, R, Roe, S., C. Friedrich, H. Burckhart, S. Panitkin, Tikhomirov, V, Salvatore, D., Mayes, JB, P. U. E. Onyisi, Garrido, M, B. Osculati, Vuillermet, R, Turra, R., M. S. Neubauer, Oda, S, Randrianarivony, K., Klimentov, A., Cowden, C, S. Kabana, Del Peso, J, Scott, W. G., F. Conventi, Le Dortz, O, Y. Coadou, Kass, R, J. Ginzburg, R. Ciftci, Darbo, G., Protopopescu, S, A. Chitan, C. Haber, R. Alon, Cobal M, D. Giugni, P. Vokac, Z. Zhao, Antos, J, Rubinskiy, I, Gorfine, G, Mandelli, L., Moore, R. W., van der Ster, D, Shao, Q. T., Alexa, C, Anulli F, Salvatore, F., S. Crépé-Renaudin, G. Negri, Bogaerts, J. A., N. Davidson, Bortfeldt, J, Kuehn, S., H. Yang, Kubota, T., Herrera, C. Mora, Schaile, D., Morettini, P, Nadal, J, Love, P. A., Bucci, F, T. J. Neep, P. Gutierrez, AbouZeid S, Harpaz, S, P. Laycock, K. Sliwa, R. D. St. Denis, Stroynowski, R, Thun, R. P., Romeo, G, J-Y. Hostachy, Torregrosa, E, Voss, R., Klinkby, E. B., D'Auria, S, M. Shiyakova, Hance, M., Mitsui, S., Ko, B, Teixeira-Dias, P, G. Alimonti, J. M. Butler, Chelstowska, M.A., Sicho, P, Z. Czyczula, Bella, L. Aperio, Clarke, RN, Esch, H, Y. Tayalati, Chiefari, G, Capriotti D, K. Kroeninger, Papadelis, A, S. M. Consonni, J. Jia, Krasznahorkay, Attila, Stanitzki, M, Karakostas, K, do Vale, M, S.w. Banerjee, Aj, Beddall, Ciapetti G, von der Schmitt, H, Leontsinis, S., Boonekamp M, Addy TN, ALOISIO, ALBERTO, M. S. Alam, P. F. Giraud, E. Coniavitis, Anghinolfi F, Aguilar Saavedra, J, Sosebee, M., C. Lapoire, Lenz, T., Lungwitz, M, Khalek, S, Petschull, D, C. P. Buszello, Renstrom, P. A. Bruckman, Haug, S., Schwegler, Ph., Shimojima, M, Bozovic Jelisavcic I, Barreiro F, R. Mandrysch, M. Lassnig, Oakes, L. B., Reisinger, I, Huegging, E, C. Petridou, P. Staroba, Paleari, C, Abramowicz, H., Ilic, N, Raas, M., Yan, Z., Yasu, Y, A. Olariu, Ishmukhametov, R., Tokushuku, K., Petridis, A., S. Kalinin, Terada, S., Cristinziani, M, A. Dafinca, Blondel, A., Le Guirriec, E., Caron, S., Luijckx, G., Maxfield, S. J., Smolek, K, K. Nagai, S. Tanaka, Barlow N, A. E. Barton, Y. S. Gao, Peso Malagón, José del, E. Devetak, Griso, S. Pagan, Wu, Y., Esposito, B., M. Ridel, Armbruster, A. J., K. Ellis, J. A. Wilson, Badescu, F, Albert, J., K. Mönig, Chapman, J, Huettmann, A., Wermes, N., Castaneda-Miranda, E, S. Pashapour, Wu, X., Washbrook, A, Koutsman, A., Matricon, P., C. Malone, Kortner, S., D. R. Quarrie, O. Bulekov, A. Coccaro, Ishino, M., D. Dobos, Miguens, J, G. Piacquadio, Arik, A, D. Berge, Torre, H., F. Prokoshin, E. Panagiotopoulou, Venturi, N., S. Hamilton, A. Manabe, Lassnig, M., Nurse, E, N. Morange, Vorwerk, V, Damazio, D, Lohse, T., S. Goldfarb, Brau, B., V. Pozdnyakov, P. Savard, Lavrijsen, W., Chekulaev, S, S. Yanush, P. Steinberg, Curatolo, M, Sjursen, T. B., Dervan, P, J. Stark, M. A. B. do Vale, Krejci, F, Giovannini, P., P. S. Miyagawa, Yarnamura, T, B. Gorini, Cavaliere V, G. Iacobucci, Canale, V, Bierwagen, K., Gazis, E, Fernando, W., A. A. Solodkov, Stoicea, G, Quadt, A., Stradling, A. R., Pedis, D., Marzano, F., Lj. Simic, Shimizu, S, Eschrich, I, Ciftci R, A. G. Olchevski, Chakraborty, D, Bolnet, N, C. Clémens, J., Hesketh, G. G., Wiglesworth, C, C. Luci, Sbrizzi, A, Rezvani, R, Radziewski, H., Bellagamba L, Azuma, Y, J. P. Thomas, Webster, J. S., R. Febbraro, Leroy, C., Mjörnmark, J. U., Chiodini, G, Moa, T., Casado, M. P., Etzion, E, Zhu, Y., M. Kaci, Stanescu-Bellu, M, J. Farley, L. P. Caloba, Chavda V, Chilingarov A, Caughron S, Robichaud-Veronneau, A., Nilsson, Björn Stefan, Binet S, D. R. Tovey, Dos Santos, S. P. A., GORINI, Edoardo, Martin, B., Jackson, J. N., Gorini, E, Volpi, M., Gorini, B, Antonov, A., M. Kado, V. Vorwerk, R. M. Fakhrutdinov, Tian, F., S. L. Wu, Cerqueira, AS, Lu, F., Aefsky, S., Wienemann, P., Klier, A, Coggeshall, J., Jez, P, J. Ernst, E. Mountricha, N. Grau, Fassi, Farida, Igonkina, O., Burckhart H, Brunet, S, B. Kaplan, Gillman, A. R., H. M. Braun, Takahashi, Y, Allport PP, Kashif, L., E. Eisenhandler, Sbarra, C., Loebinger, F, Bundock, A. C., Sansoni, A, Dueren, M, Cole, S., D. Lellouch, Pernegger, H., Silverstein, Samuel B.,, P. . A. . B. De Renstrom, Byszewski M, H. Boterenbrood, Manabe, A., Virchaux, M, Dearnaley, W, Belanger-Champagne C, O. Sasaki, Kama, S., Tua, A, Vlasak, M, Fabbri, L, Volpi, G., Gaponenko, A., Oram, C, Tsiakiris, M., van Huysduynen, L, R. Nicolaidou, N. Zhou, Benchekroun, D, Johansson, K, Johansson, P, F. Djama, M. Lichtnecker, Grinstein, S., Takeda, H., K. Copic, T. M. Hong, Nash, M., G. Vegni, M. Simonyan, Hadley, D, A. Gemmell, J. C. Vermeulen, Davies, E., Bawa, H   +999 more
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Experimental and theoretical high energy physics research. [UCLA] [PDF]

, 1992
Progress in the various components of the UCLA High-Energy Physics Research program is summarized, including some representative figures and lists of resulting presentations and published papers. Principal efforts were directed at the following: (I) UCLA

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