Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Solid oxide steam electrolysis for high temperature hydrogen production [PDF]
This study has focused on solid oxide electrolyser cells for high temperature steam electrolysis. Solid oxide electrolysis is the reverse operation of solid oxide fuel cells (SOFC), so many of the same component materials may be used.
Eccleston, Kelcey L.
core +2 more sources
High-entropy glass materials: formation mechanisms, processing pathways, and emerging applications
High-entropy glass materials are gaining attention because they combine useful properties for energy, electronic, and biomedical applications. Building on crystalline high-entropy alloys, the introduction of amorphous multi-component structures opens new
Yongxing Hu +8 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Effect of Sc/Y Co-Doping on Microstructure and High-Temperature Oxidation Properties of FeCoNiCrAl High-Entropy Alloys [PDF]
To improve the oxidation resistance of FeCoNiCrAl high-entropy alloy in high-temperature environments, Sc/Y was co-doped in FeCoNiCrAl alloy.The high-entropy alloys FeCoNiCrAl and FeCoNiCrAlScY were prepared by vacuum induction melting method, and the ...
LI Dongqing, ZHENG Shuhui, GU Jian, LIU Shengchun, SI Jiajun
doaj +1 more source
High‐entropy oxide: A future anode contender for lithium‐ion battery
Revolutionary changes in energy storage technology have put forward higher requirements on next‐generation anode materials for lithium‐ion battery. Recently, a new class of materials with complex stoichiometric ratios, high‐entropy oxide (HEO), has ...
Xuefeng Liu +6 more
doaj +1 more source
Localisation of vibrational modes in high-entropy oxides
Abstract The recently-discovered high-entropy oxides (HEO’s) offer a paradoxical combination of crystalline arrangement and high disorder. They differ qualitatively from established paradigms for disordered solids such as glasses and alloys. In these latter systems, it is well known that disorder induces localised vibrational excitations.
C M Wilson, R Ganesh, D A Crandles
openaire +3 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Self-repairing high entropy oxides
12 pages,4 ...
Liu, Zongwen +22 more
openaire +2 more sources
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source

