Results 131 to 140 of about 1,713,151 (356)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Design Considerations on Voltage and Current Transfer Ratio of High-Frequency Transformers

CSEE Journal of Power and Energy Systems
A high frequency (HF) transformer is key equipment for dc-dc converter to achieve galvanic isolation and voltage transformation. As operating frequency increases, voltage and current transfer ratio of HF transformer may significantly deviate from the ...
Chen Liu, Lei Qi, Xiang Cui
doaj   +1 more source

Flexible Power Electronic Transformer for Power Flow Control Applications [PDF]

Journal of Operation and Automation in Power Engineering, 2007
This paper proposes a Flexible Power Electronic Transformer (FPET) for the application in the micro-grids. The low frequency transformer is usually used at the Point of Common Coupling (PCC) to connect the low voltage grid and utility network to each ...
J. Fallah Ardeshir, A. Ajami, A. Jalilvand, A. Mohammadpour   +3 more
doaj  

Calculation of core loss and copper loss in amorphous/nanocrystalline core-based high-frequency transformer

, 2016
Amorphous and nanocrystalline alloys are now widely used for the cores of high-frequency transformers, and Litz-wire is commonly used as the windings, while it is difficult to calculate the resistance accurately.
Xiaojing Liu, Youhua H. Wang, Jianguo Zhu, Youguang Guo, G. Lei, Chengcheng Liu   +5 more
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A high voltage gain solid-state transformer for integration of renewable energy and AC sources

Scientific Reports
This paper introduces a novel high-voltage gain topology for a solid-state transformer, integrating a DC-DC converter and dual active bridge converters. The proposed design features three DC links operating at different voltage levels.
Seyed Majid Hashemzadeh, Mohammed A. Al-Hitmi, Shirazul Islam, Atif Iqbal, Hadi Aghaei, Seyed Hossein Hosseini, Ebrahim Babaei   +6 more
doaj   +1 more source

Technical and vocational skills (TVS): a means of preventing violence among youth in Nigeria [PDF]

, 2017
Technical and vocational skills are an important tool for reducing violence among youth, especially in Nigeria, who face security challenges due to different kinds of violence.
Ibrahim, Mohammed, Wan Mohamed, Wan Azlinda   +1 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Design considerations for large space electric power systems [PDF]

As power levels of spacecraft rise to the 50 to 100 kW range, it becomes apparent that low voltage (28 V) dc power distribution and management systems will not operate efficiently at these higher power levels.
Finke, R. C., Hansen, I. G., Renz, D. D., Stevens, N. J., Triner, J. E.   +4 more
core   +1 more source