Results 81 to 90 of about 20,225 (295)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Conversores CC-CC bidirecionais isolados simétricos com baixa ondulação de corrente [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2015Neste trabalho e apresentado o estudo de uma família de conversores CC-CC bidirecionais baseada na ...
Souza, Eduardo Valmir de
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A Novel Improved Voltage Gain and Reduced Voltage Stress Unidirectional DC/DC Converter for Electric Vehicle Battery Charging System

IEEE Access
The technology of electric vehicle transport is always evolving. In electric automobiles, battery charging is an essential requirement. The requirement for a high gain DC/DC converter exists in electric vehicle battery charging systems to align the ...
Nalluri Ramya Sri, M. Praveen Kumar
doaj   +1 more source

A Novel Boost Conversion with High Voltage Ratio

MATEC Web of Conferences, 2017
When the traditional Boost converter duty cycle exceeds a certain value, the output voltage is not only increased, but will be reduced. Therefore, a new Boost converter with intermediate tap is proposed.
Chai Yu, Li Xiaonan
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

An Ultra High Gain Converter for Driving HASEL Actuator Used in Soft Mobile Robots. [PDF]

Biomimetics (Basel), 2023
Lodh T, Le HP.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Optimized Interleaved Ultra-High Gain DC-DC Power Converter With Low Ripple Input Current and Voltage Stress for Fuel Cell Systems

IEEE Access
This paper presents an ultra-high voltage gain power converter designed to address the challenges posed by the inherently low output voltage and high output current of fuel cell systems.
Izaac K. Denholm, Waqas Hassan, Michael Negnevitsky, Dylan D.-C. Lu   +3 more
doaj   +1 more source

Magnetically coupled high-gain Y-source isolated DC/DC converter

, 2014
A new form of magnetically coupled DC/DC converter is proposed for medium power applications (250 W to 2 kW), requiring a high-voltage gain, short inductive charging time and galvanic isolation.
Loh, Poh Chiang, Town, Graham, Siwakoti, YP, Siwakoti, Yam P., Blaabjerg, Frede; id_orcid, Blaabjerg, F, Loh, PC, Town, GE   +7 more
core   +1 more source