Results 191 to 200 of about 17,843,189 (247)

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

Protocol for high‐intensity focused ultrasound (HIFU) treatment of cutaneous neurofibromas

JEADV Clinical Practice
Mimmi Tang, Katrine Elisabeth Karmisholt, Martin Gillstedt, Jaishri O. Blakeley, Joshua Roberts, Jørgen Serup, Torsten Bove, Sirkku Peltonen   +7 more
doaj   +1 more source

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High-intensity focused ultrasound therapy

Best Practice and Research in Clinical Obstetrics and Gynaecology, 2018
High-intensity focused ultrasound therapy has received increasing interest in the management of benign uterine tumors. Either magnetic resonance or ultrasound imaging has been used to target and monitor the ablation process. This article provides an overview of the background, clinical use, treatment outcomes, and safety of high-intensity focused ...
Cheung Vyt
exaly   +3 more sources

High-intensity focused ultrasound

Nihon rinsho. Japanese journal of clinical medicine, 2012
Focal therapy (FT) is an emerging noncancerous tissue preservation strategy that aims for treating only the areas of cancer. FT has attracted attention over the several years in the field of treatment of localized prostate cancer. On the other hand, the use of minimally invasive ablative techniques in the management of patients with low-grade and ...
Satoru Muto, Shigeo Horie
openaire   +3 more sources

High-Intensity Focused Ultrasound

Gastrointestinal Endoscopy Clinics of North America, 1994
High-intensity focused ultrasound (HIFU) is a technology that permits the use of ultrasound waves used for imaging and then focuses them as one would use a magnifying glass to focus sunlight. The ultrasound energy is absorbed by tissue and converted to heat and can be used to ablate tissue.
N T, Sanghvi, R H, Hawes
openaire   +2 more sources

High-intensity focused ultrasound for prostate cancer

Expert Review of Medical Devices, 2020
High-intensity focused ultrasound (HIFU) is a noninvasive procedure that has shown promising results in a wide range of malignant and nonmalignant conditions, including localized prostate cancer (PCa). This review aims to describe the application of HIFU in the management of patients with PCa, explaining its basic therapeutic principles, going through ...
Napoli, Alessandro, Alfieri, Giulia, Scipione, Roberto, Leonardi, Andrea, Fierro, Davide, Panebianco, Valeria, De Nunzio, Cosimo, Leonardo, Costantino, Catalano, Carlo   +8 more
openaire   +2 more sources

Hemostasis using high intensity focused ultrasound

European Journal of Ultrasound, 1999
High intensity focused ultrasound (HIFU) has been shown to be an effective method of hemostasis, in animal studies, for both solid organs and blood vessels. Two distinct effects of HIFU, thermal and mechanical, appear to contribute to hemostasis. Acoustic hemostasis may provide an effective method in surgery and prehospital settings for treating trauma
S, Vaezy, R, Marti, P, Mourad, L, Crum
openaire   +2 more sources