Results 1 to 10 of about 20,532,578 (234)

Implementation of an Open-Source Multiplexing Ion Gate Control for High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS). [PDF]

J Am Soc Mass Spectrom, 2023
With ion mobility spectrometry increasingly used in mass spectrometry to enhance separation by increasing orthogonality, low ion throughput is a challenge for the drift-tube ion mobility experiment. The High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) is no exception and routinely uses duty cycles of less than 0.1%. Multiplexing techniques such
Naylor CN, Clowers BH, Schlottmann F, Solle N, Zimmermann S.   +4 more
europepmc   +9 more sources

Detection of Triacetone Triperoxide by High Kinetic Energy Ion Mobility Spectrometry. [PDF]

Anal Chem, 2023
High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) is a versatile technique for the detection of gaseous target molecules that is particularly useful in complex chemical environments, while the instrumental effort is low. Operating HiKE-IMS at reduced pressures from 10 to 60 mbar results in fewer ion-neutral collisions than at ambient pressure ...
Schaefer C, Lippmann M, Beukers M, Beijer N, van de Kamp B, Knotter J, Zimmermann S.   +6 more
europepmc   +7 more sources

Revealing the Ion Chemistry Occurring in High Kinetic Energy-Ion Mobility Spectrometry: A Proof of Principle Study

Analytica, 2023
Here, we present proof of principle studies to demonstrate how the product ions associated with the ion mobility peaks obtained from a High Kinetic Energy-Ion Mobility Spectrometer (HiKE-IMS) measurement of a volatile can be identified using a Proton ...
Florentin Weiss, Christoph Schaefer, Stefan Zimmermann, Tilmann D. Märk, Chris A. Mayhew   +4 more
doaj   +5 more sources

Positive Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
In contrast to classical Ion Mobility Spectrometers (IMS) operating at ambient pressure, the High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) is operated at reduced pressures of between 10 and 40 mbar and higher reduced electric field strengths of up to 120 Td.
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +4 more sources

Reliable Detection of Chemical Warfare Agents Using High Kinetic Energy Ion Mobility Spectrometry. [PDF]

J Am Soc Mass Spectrom
High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) ionize and separate ions at reduced pressures of 10–40 mbar and over a wide range of reduced electric field strengths E/N of up to 120 Td. Their reduced operating pressure is distinct from that of conventional drift tube ion mobility spectrometers that operate at ambient pressure for trace ...
Schaefer C, Allers M, Hitzemann M, Nitschke A, Kobelt T, Mörtel M, Schröder S, Ficks A, Zimmermann S.   +8 more
europepmc   +4 more sources

Negative Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
Due to the operation at background pressures between 10-40 mbar and high reduced electric field strengths of up to 120 Td, the ion–molecule reactions in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) differ from those in classical ambient pressure IMS.
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +4 more sources

Field-Dependent Reduced Ion Mobilities of Positive and Negative Ions in Air and Nitrogen in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
In High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS), ions are formed in a reaction region and separated in a drift region, which is similar to classical drift tube ion mobility spectrometers (IMS) operated at ambient pressure. However, in contrast to the latter, the HiKE-IMS is operated at a decreased background pressure of 10–40 mbar and ...
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +4 more sources

High Kinetic Energy Ion Mobility Spectrometry – Mass Spectrometry investigations of four inhalation anaesthetics: isoflurane, enflurane, sevoflurane and desflurane

International Journal of Mass Spectrometry, 2022
Here we report the first High Kinetic Energy-Ion Mobility Spectrometry-Mass Spectrometric (HiKE-IMSMS) investigations involving four fluranes; isoflurane, enflurane, sevoflurane and desflurane. Unlike standard (atmospheric pressure) IMS, HiKEIMS can detect these compounds in positive ion mode. This is because its low-pressure environment (similar to 14
Gary Eiceman, Veronika Ruzsanyi, Stefan Zimmermann   +2 more
exaly   +5 more sources

Influence of Sample Gas Humidity on Product Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS)

Journal of the American Society for Mass Spectrometry, 2022
High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) chemically ionize gaseous samples via reactant ions and separate the generated ions by their motion in a neutral gas under the influence of an electric field. Operation at reduced pressures of 10–40 mbar allows for reaching high reduced electric field strengths (E/N) of up to 120 Td.
Ansgar T Kirk, Stefan Zimmermann, Christoph Schafer   +2 more
exaly   +4 more sources

Influence of Reduced Field Strength on Product Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS)

Journal of the American Society for Mass Spectrometry, 2021
Classical ion mobility spectrometers (IMS) operated at ambient pressure, often use atmospheric pressure chemical ionization (APCI) sources to ionize organic compounds. In APCI, reactant ions ionize neutral analyte molecules via gas-phase ion–molecule reactions. The positively charged reactant ions in purified, dry air are H3O+, NO+, and O2+•.
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +4 more sources