Implementation of an Open-Source Multiplexing Ion Gate Control for High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS). [PDF]
J Am Soc Mass Spectrom, 2023 With ion mobility spectrometry increasingly used in mass spectrometry to enhance separation by increasing orthogonality, low ion throughput is a challenge for the drift-tube ion mobility experiment. The High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) is no exception and routinely uses duty cycles of less than 0.1%. Multiplexing techniques such
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Detection of Triacetone Triperoxide by High Kinetic Energy Ion Mobility Spectrometry. [PDF]
Anal Chem, 2023 High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) is a versatile technique for the detection of gaseous target molecules that is particularly useful in complex chemical environments, while the instrumental effort is low. Operating HiKE-IMS at reduced pressures from 10 to 60 mbar results in fewer ion-neutral collisions than at ambient pressure ...
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Revealing the Ion Chemistry Occurring in High Kinetic Energy-Ion Mobility Spectrometry: A Proof of Principle Study [PDF]
Analytica, 2023 Here, we present proof of principle studies to demonstrate how the product ions associated with the ion mobility peaks obtained from a High Kinetic Energy-Ion Mobility Spectrometer (HiKE-IMS) measurement of a volatile can be identified using a Proton ...
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Positive Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]
Journal of the American Society for Mass Spectrometry, 2020 In contrast to classical Ion Mobility Spectrometers (IMS) operating at ambient pressure, the High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) is operated at reduced pressures of between 10 and 40 mbar and higher reduced electric field strengths of up to 120 Td.
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Negative Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]
Journal of the American Society for Mass Spectrometry, 2020 Due to the operation at background pressures between 10-40 mbar and high reduced electric field strengths of up to 120 Td, the ion–molecule reactions in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) differ from those in classical ambient pressure IMS.
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The origin of isomerization of aniline revealed by high kinetic energy ion mobility spectrometry (HiKE-IMS) [PDF]
Physical Chemistry Chemical Physics, 2023 Three ion mobility peaks of 4-fluoroaniline, including the para -protonated and molecular ion species, when measured with a high-kinetic energy ion mobility spectrometer and peak abundances depend only on the ionization settings.
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Field-Dependent Reduced Ion Mobilities of Positive and Negative Ions in Air and Nitrogen in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]
Journal of the American Society for Mass Spectrometry, 2020 In High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS), ions are formed in a reaction region and separated in a drift region, which is similar to classical drift tube ion mobility spectrometers (IMS) operated at ambient pressure. However, in contrast to the latter, the HiKE-IMS is operated at a decreased background pressure of 10–40 mbar and ...
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High Kinetic Energy Ion Mobility Spectrometry – Mass Spectrometry investigations of four inhalation anaesthetics: isoflurane, enflurane, sevoflurane and desflurane [PDF]
International Journal of Mass Spectrometry, 2022 Here we report the first High Kinetic Energy-Ion Mobility Spectrometry-Mass Spectrometric (HiKE-IMSMS) investigations involving four fluranes; isoflurane, enflurane, sevoflurane and desflurane. Unlike standard (atmospheric pressure) IMS, HiKEIMS can detect these compounds in positive ion mode. This is because its low-pressure environment (similar to 14
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Pursuing drug laboratories: Analysis of drug precursors with High Kinetic Energy Ion Mobility Spectrometry [PDF]
Forensic Science InternationalHigh Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) is a technique for rapid and reliable detection of trace compounds down to ppbV-levels within one second. Compared to classical IMS operating at ambient pressure and providing the ion mobility at low electric fields, HiKE-IMS can also provide the analyte-specific field dependence of the ion ...
Stefan Zimmermann +2 more
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Reliable Detection of Chemical Warfare Agents Using High Kinetic Energy Ion Mobility Spectrometry. [PDF]
J Am Soc Mass SpectromHigh Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) ionize and separate ions at reduced pressures of 10–40 mbar and over a wide range of reduced electric field strengths E/N of up to 120 Td. Their reduced operating pressure is distinct from that of conventional drift tube ion mobility spectrometers that operate at ambient pressure for trace ...
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