Results 1 to 10 of about 51,857 (137)

Implementation of an Open-Source Multiplexing Ion Gate Control for High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2023
With ion mobility spectrometry increasingly used in mass spectrometry to enhance separation by increasing orthogonality, low ion throughput is a challenge for the drift-tube ion mobility experiment. The High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) is no exception and routinely uses duty cycles of less than 0.1%. Multiplexing techniques such
Stefan Zimmermann, Cameron Naylor, Brian Clowers   +2 more
exaly   +11 more sources

Positive Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
In contrast to classical Ion Mobility Spectrometers (IMS) operating at ambient pressure, the High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) is operated at reduced pressures of between 10 and 40 mbar and higher reduced electric field strengths of up to 120 Td.
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +6 more sources

Negative Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
Due to the operation at background pressures between 10-40 mbar and high reduced electric field strengths of up to 120 Td, the ion–molecule reactions in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) differ from those in classical ambient pressure IMS.
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +6 more sources

High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) at 40 mbar [PDF]

Journal of the American Society for Mass Spectrometry, 2020
High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) are usually operated at an absolute pressure of 20 mbar reaching high reduced electric field strengths of up to 125 Td for controlled reaction kinetics. This significantly increases the linear range and limits chemical cross sensitivities.
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +6 more sources

The origin of isomerization of aniline revealed by high kinetic energy ion mobility spectrometry (HiKE-IMS) [PDF]

Physical Chemistry Chemical Physics, 2023
Three ion mobility peaks of 4-fluoroaniline, including the para-protonated and molecular ion species, when measured with a high-kinetic energy ion mobility spectrometer and peak abundances depend only on the ionization settings.
Ansgar T Kirk, Stefan Zimmermann, Cameron Naylor   +2 more
exaly   +5 more sources

Field-Dependent Reduced Ion Mobilities of Positive and Negative Ions in Air and Nitrogen in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) [PDF]

Journal of the American Society for Mass Spectrometry, 2020
In High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS), ions are formed in a reaction region and separated in a drift region, which is similar to classical drift tube ion mobility spectrometers (IMS) operated at ambient pressure. However, in contrast to the latter, the HiKE-IMS is operated at a decreased background pressure of 10–40 mbar and ...
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +6 more sources

Ion Mobility Shift of Isotopologues in a High Kinetic Energy Ion Mobility Spectrometer (HiKE-IMS) at Elevated Effective Temperatures [PDF]

Journal of the American Society for Mass Spectrometry, 2020
Ion mobility spectrometers (IMS) separate ions mainly by ion–neutral collision cross section and to a lesser extent by ion mass and effective temperature. When investigating isotopologues, the difference in collision cross section can be assumed negligible.
Ansgar T Kirk, Maria Allers, Stefan Zimmermann   +2 more
exaly   +6 more sources

Revealing the Ion Chemistry Occurring in High Kinetic Energy-Ion Mobility Spectrometry: A Proof of Principle Study

Analytica—A Journal of Analytical Chemistry and Chemical Analysis, 2023
Here, we present proof of principle studies to demonstrate how the product ions associated with the ion mobility peaks obtained from a High Kinetic Energy-Ion Mobility Spectrometer (HiKE-IMS) measurement of a volatile can be identified using a Proton ...
Stefan Zimmermann, Chris Mayhew, Christoph Schafer   +2 more
exaly   +3 more sources

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Fundamental Challenges, Physical Implementations, and Integration Strategies for Ising Machines in Large‐Scale Optimization Tasks

Advanced Electronic Materials, EarlyView.
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley   +1 more source