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High Kinetic Energy Ion Mobility Spectrometry: A Promising Approach for Fast and Reliable Detection of Chemical Warfare Agents

2023 IEEE SENSORS, 2023
Ion mobility spectrometry (IMS) is a well-known technique for the detection of chemical warfare agents, other highly toxic compounds, drugs of abuse and explosives, since IMS have low detection limits in the pptV-range, short response times of just few ...
Stefan Zimmermann   +2 more
exaly   +4 more sources

High Kinetic Energy Ion Mobility Spectrometer: Quantitative Analysis of Gas Mixtures with Ion Mobility Spectrometry

Analytical Chemistry, 2014
We present a high kinetic energy ion mobility spectrometer (HiKE-IMS) for quantitative gas analysis. Drift tube and reaction tube can be operated at reduced fields up to 110 Td. At such conditions the distribution of reactant ion water clusters is shifted toward smaller clusters.
Ansgar T Kirk   +2 more
exaly   +4 more sources

High-Resolution High Kinetic Energy Ion Mobility Spectrometer Based on a Low-Discrimination Tristate Ion Shutter

open access: yesAnalytical Chemistry, 2018
High kinetic energy ion mobility spectrometry (HiKE-IMS) allows for sensitive trace gas analysis within seconds, mitigating many disadvantages of standard ion mobility spectrometers through operation at reduced pressure and high electric field strengths.
Ansgar T Kirk   +2 more
exaly   +5 more sources

Detection of Volatile Toxic Industrial Chemicals with Classical Ion Mobility Spectrometry and High-Kinetic Energy Ion Mobility Spectrometry

Analytical Chemistry, 2021
Due to their high sensitivity and compact design, ion mobility spectrometers are widely used to detect toxic industrial chemicals (TICs) in air. However, when analyzing complex gas mixtures, classical ion mobility spectrometry (IMS) suffers from false-positive rates due to limited resolving power or false-negative rates caused by competitive ion ...
Maria Allers   +7 more
openaire   +3 more sources

Analyzing Positive Reactant Ions in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS) by HiKE-IMS–MS

Journal of the American Society for Mass Spectrometry, 2020
In contrast to classical ion mobility spectrometers (IMS) operating at ambient pressure, the high kinetic energy ion mobility spectrometer (HiKE-IMS) is operated at reduced pressures between 10-40 mbar. In HiKE-IMS, ions are generated in a reaction region before they are separated in a drift region.
Maria Allers   +7 more
openaire   +3 more sources

Simulation of Cluster Dynamics of Proton-Bound Water Clusters in a High Kinetic Energy Ion-Mobility Spectrometer.

Journal of the American Society for Mass Spectrometry, 2021
Ions are separated in ion mobility spectrometry (IMS) by their characteristic motion through a gas-filled drift tube with a static electric field present. Chemical dynamics, such as clustering and declustering of chemically reactive systems, and physical
Duygu Erdogdu   +6 more
semanticscholar   +1 more source

Tracking Isomerizations of High-Energy Adenine Cation Radicals by UV-Vis Action Spectroscopy and Cyclic Ion Mobility Mass Spectrometry.

Journal of Physical Chemistry A, 2023
We report experimental and computational studies of protonated adenine C-8 σ-radicals that are presumed yet elusive reactive intermediates of oxidative damage to nucleic acids.
V. Zima   +4 more
semanticscholar   +1 more source

Energy-Resolved Ion Mobility Spectrometry: Composite Breakdown Curves for Distinguishing Isomeric Product Ions.

Journal of the American Society for Mass Spectrometry, 2022
Identification of lipopeptides (LpAA) synthesized from bacteria involves the study of structural characterization. Twenty LpAA have been characterized using commercial tandem high-resolution mass spectrometers in negative electrospray, employing ...
Amandine Hueber   +7 more
semanticscholar   +1 more source

High-Definition Differential Ion Mobility Spectrometry with Structural Isotopic Shifts for Anionic Compounds.

Journal of the American Society for Mass Spectrometry, 2023
Differential ion mobility spectrometry (FAIMS) had emerged in the 2000s as a novel tool for postionization separations in conjunction with mass spectrometry (MS). High-definition FAIMS introduced a decade ago has enabled resolution of peptide, lipid, and
Pratima Pathak, A. Shvartsburg
semanticscholar   +1 more source

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