Results 81 to 90 of about 22,385,248 (304)

HACPar: An efficient parallel multiscale framework for hybrid atomistic–continuum simulation at the micro- and nanoscale

open access: yesAdvances in Mechanical Engineering, 2017
The hybrid atomistic–continuum coupling method based on domain decomposition serves as an important tool for the microfluidic simulation. However, major modifications to existing codes are often required to enable such simulations, which pose significant
Xiao-Guang Ren   +4 more
doaj   +1 more source

Traffic Sign Detection Method Based on Improved SSD

open access: yesInformation, 2020
Due to changes in illumination, adverse weather conditions, and interference from signs similar to real traffic signs, the false detection of traffic signs is possible. Nevertheless, in order to improve the detection effect of small targets, baseline SSD
Shuai You   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Performance Evaluation and Energy Efficiency of High-Density HPC Platforms Based on Intel, AMD and ARM Processors

open access: yes, 2013
peer reviewedDue to growth of energy consumption by HPC servers and data centers many research efforts aim at addressing the problem of energy efficiency.
Oleksiak, A.   +7 more
core   +1 more source

xLSTM-Based Urban Traffic Flow Prediction for Intelligent Transportation Governance

open access: yesApplied Sciences
Urban traffic congestion poses persistent challenges to mobility, public safety, and governance efficiency in metropolitan areas. This study proposes an intelligent traffic flow forecasting framework based on an extended Long Short-Term Memory (xLSTM ...
Chung-I Huang   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

High Performance Computing and Communications Panel Report

open access: yes, 1992
The High Performance Computing and Communications (HPCC) Initiative was launched in 1992 by President George H.W. Bush in an effort to secure and extend U.S. leadership in advanced technologies.
PCAST Panel on High Performance Computing and Communications   +2 more
core  

Ensemble of rankers for efficient gene signature extraction in smoke exposure classification

open access: yesBMC Bioinformatics, 2018
Background System toxicology aims at understanding the mechanisms used by biological systems to respond to toxicants. Such understanding can be leveraged to assess the risk of chemicals, drugs, and consumer products in living organisms.
Maurizio Giordano   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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