Results 211 to 220 of about 693,447 (358)

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Development, validation and application of a high-performance liquid chromatography method for the detection of ibuprofen in elephant plasma. [PDF]

Heliyon
Cox S, Bloom A, Golias R, Duncan M, Bergman J, Cushing A.   +5 more
europepmc   +1 more source

Peptide Display Directed Assembly of Biopolymer Core–Silica Shell Particles

Advanced Healthcare Materials, EarlyView.
Bacterial cells are engineered to produce biopolyester particles displaying peptides mediating growth of silica. Peptide‐coated biopolyester particles are treated with silica precursors and silica shell formation is studied. Transmission electron microscopy shows silica‐coated BPs which are formed after the silicification treatment. Characterization of
Deeptee Chandrashekhar Pande, Frank Sainsbury, Bernd H. A. Rehm   +2 more
wiley   +1 more source

Triphenyl-Modified Mixed-Mode Stationary Phases With and Without Embedded Ion-Exchange Sites for High-Performance Liquid Chromatography. [PDF]

J Sep Sci
Wolter M, Maalouf M, Janek M, Knappe C, Kramer M, Lämmerhofer M.   +5 more
europepmc   +1 more source

Analysis of corticosteroids in biological fluids by high-performance liquid chromatography with fluorometric detection.

, 1988
Ayako SUDO
openalex   +2 more sources

Integration of Bioengineered Tools in Assisted Reproductive Technologies

Advanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak, Edith Coonen, Ron van Golde, Erik Vrij   +3 more
wiley   +1 more source

High-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of 23 antidepressants and active metabolites in human serum and its application in therapeutic drug monitoring. [PDF]

Front Pharmacol
Wang J, Wang J, Zhang C, Li G.
europepmc   +1 more source

Fluorescence high-performance liquid chromatography of icosapentaenoic acid and arachidonic acid in ovary and testis of several fishes and plankton lived in the sea area of Micronesia.

, 1986
Norio Ichinose, S. Abe, Kyoko Adachi, Ryusuke KATO   +3 more
openalex   +2 more sources

Coagulation Matters: ATIII‐Enriched Biomolecular Corona Enhances the Hemocompatibility of PEG Nanoparticles

Advanced Healthcare Materials, EarlyView.
Engineering of a functional protein corona with a synergistic heparin‐ATIII complex significantly improves hemocompatibility of PEG nanoparticles. Through deliberate engineering of the protein corona, a 4‐fold reduction in coagulation activation (F1 + 2) without inducing adverse thromboinflammatory reactions (CD11b, C5a) is achieved without disrupting ...
Vaidehi Londhe, Manfred F. Maitz, Triantafyllos Chavakis, Carsten Werner, Alessia C. G. Weiss, Quinn A. Besford   +5 more
wiley   +1 more source

A Systematic Profiling of the Components of Kukeya Tablets, a Traditional Ethnic Medicine Prescription, by Ultra-High-Performance Liquid Chromatography-Quadrupole/Orbitrap High-Resolution Mass Spectrometry. [PDF]

Pharmaceuticals (Basel)
Kahaer G, Muhetaer M, Abdulla R, Wu T, Luo Y, Aisa HA.   +5 more
europepmc   +1 more source