Results 211 to 220 of about 1,087,009 (341)

Network pharmacology combined with ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry method to explore the mechanism of Shizhi Fang in treating uric acid nephropathy mice. [PDF]

J Tradit Chin Med
Feng Y, Xuming Z, Zhiyuan WU, Jiandong G.   +3 more
europepmc   +1 more source

Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin‐Derived IKVAV Peptides

Advanced Healthcare Materials, EarlyView.
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns, Joost A. P. M. Wijnakker, Victor A. Veenbrink, Riccardo Bellan, Fenna W. B. Craenmehr, Simone I. S. Hendrikse, Johnick F. van Sprang, Wim de Lau, E. W. Meijer, Hans Clevers, Patricia Y. W. Dankers   +10 more
wiley   +1 more source

Offline comprehensive liquid chromatography in combination with a Deoxyribonuclease I immobilized enzymatic reactor for selective screening of oligonucleotide mixtures [PDF]

, 2016
Alvarez Porebski, Piotr Wiktor, Lynen, Frederic   +1 more
core   +1 more source

Simultaneous Detection and Quantification of Organic Acids and Furans in Lignocellulosic Biomass Hydrolysate Through High-Performance Liquid Chromatography With Diode Array Detector. [PDF]

J Sep Sci
Casella P, Loffredo R, Rao MA, Liuzzi F, De Bari I, Molino A.   +5 more
europepmc   +1 more source

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, Joshua Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Optimization and Validation of a High-Performance Liquid Chromatography (HPLC-UV) Method for Quantification of α-Lipoic Acid in Cyclodextrins Complex for Ocular Delivery. [PDF]

Biomed Chromatogr
Ta PL, Bernat-Just L, Alambiaga-Caravaca AM, Rodilla V, López-Castellano A, Bosch-Morell F.   +5 more
europepmc   +1 more source

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source

Metabolomic analysis of fatal hypothermia using ultra-high-performance liquid chromatography‒mass spectrometry. [PDF]

Front Mol Biosci
Li JH, Liu JL, Song JW, Deng WL, Cao XZ, Wu ZW, Chen DH, Wang H, Yu S, Wang Q.   +9 more
europepmc   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Enantioseparation of Mirabegron Using Cyclodextrin-based Chiral Columns: High-performance Liquid Chromatography and Molecular Modeling Study. [PDF]

J Sep Sci
Mhammad A, Dombi G, Dobó M, Szabó ZI, Fiser B, Tóth G.   +5 more
europepmc   +1 more source