Results 101 to 110 of about 9,447,834 (313)

Analysis and suppression method of synchronous frequency resonance for self-synchronizing voltage source inverter

open access: yesInternational Journal of Electrical Power & Energy Systems
Self-synchronizing voltage source inverter (SSVSI) can effectively improve grid frequency stability. However, the synchronous frequency resonance (SFR) inevitably exists in SSVSI.
Youze Fu   +7 more
doaj   +1 more source

Femtosecond Laser Fabrication of Anatase TiO2 Micro-nanostructures with Chemical Oxidation and Annealing

open access: yesScientific Reports, 2017
The fabrication of nanoporous anatase TiO2 on a microstructured Ti base is achieved through an innovative hybrid fabrication method involving femtosecond laser ablation coupled with H2O2 oxidation and annealing. The anatase TiO2 micro-nanostructures have
Ting Huang   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Multiscale electromagnetic–thermal–fluid field coupling model for oil-immersed transformers

open access: yesFrontiers in Mechanical Engineering
Accurate predictions of the hotspot temperatures within large oil-immersed transformers are critical to their operational safety and longevity. The present work explores a novel multiscale electromagnetic–thermal–fluid indirect coupling model to address ...
Mingzhi Peng   +5 more
doaj   +1 more source

Creeping flashover characteristics improvement of nanofluid/pressboard system with TiO2 nanoparticles

open access: yesAIP Advances, 2018
Creeping flashover easily occurs at the interface between oil and pressboard in transformer and thus results in outage of power transmission system. Investigations have shown that creeping flashover characteristics at oil/pressboard interface can be ...
Meng Huang   +5 more
doaj   +1 more source

Towards Quantitative Simulations of High Power Proton Cyclotrons

open access: yes, 2010
PSI operates a cyclotron based high intensity proton accelerator routinely at an average beam power of 1.3MW. With this power the facility is at the worldwide forefront of high intensity proton accelerators.
Adelmann, A.   +6 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

The development of an intelligent comprehensive detection instrument for circuit breakers in power systems and its key technologies

open access: yesEnergy Informatics
To improve the accuracy and reliability of circuit breaker detection in power systems, this study proposes an intelligent detection instrument. The instrument addresses key issues found in traditional methods, such as limited real-time performance ...
Weimin Guan, Han Hu, Chao Sun, Jie Ji
doaj   +1 more source

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