Results 51 to 60 of about 17,871,055 (309)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Development of a High-Switching-Frequency Motor Controller Based on SiC Discrete Components

open access: yesWorld Electric Vehicle Journal
Discrete Silicon Carbide Metal-Oxide-Semiconductor Field-Effect Transistors (SiC MOSFETs) are characterized by their lower parasitic parameters and single-chip design, enabling them to achieve even faster switching speeds.
Shaokun Zhang, Jing Guo, Wei Sun
doaj   +1 more source

Automated alignment of fast-axis collimator lenses for high-power diode laser bars

open access: yes, 2022
Paper 89650VThe active alignment of fast axis collimator lenses (FAC) is the most challenging part in the manufacturing process of optical systems based on high power diode laser bars.
Traub, M.   +4 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Wave Energy Conversion Technology Based on Liquid Metal Magnetohydrodynamic Generators and Its Research Progress

open access: yesEnergies
Wave energy is a highly concentrated energy resource with five times higher energy density than wind and at least ten times the power density of solar energy.
Lingzhi Zhao, Aiwu Peng
doaj   +1 more source

Compact, ultra-high vacuum compatible, high power density conductive heaters

open access: yesAIP Advances, 2023
We present a design and evaluation of a simple and easy-to-fabricate conductive heater intended for ultra-high vacuum experiments. We demonstrate a compact and power-dense heater that has minimal outgassing up to nearly 200 °C. We further detail a method
Rudolph N. Kohn Jr.   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Experimental Study of an Evaporative Cooling System in a Rotating Vertical Channel with a Circular Cross-Section for Large Hydro-Generators

open access: yesEnergies
With the evolution of hydroelectric generators toward larger capacity and higher rotational speeds, the significa++nt increase in power density has rendered rotor cooling technology a critical bottleneck restricting performance enhancement.
Ruiwei Li, Lin Ruan
doaj   +1 more source

A high power density single flow zinc-nickel battery with three-dimensional porous negative electrode

open access: yes, 2013
Low power density (operated current density) is one critical obstacle to the development of single flow zinc nickel batteries (ZNBs). Three-dimensional porous nickel foams (NFs) are first introduced to ZNBs to improve power density.
Zhang, Liqun   +7 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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