Results 41 to 50 of about 1,123,025 (269)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Optimization of Tungsten Heavy Alloy Cutting Parameters Based on RSM and Reinforcement Dung Beetle Algorithm

Sensors, 2023
Tungsten heavy alloys (WHAs) are an extremely hard-to-machine material extensively used in demanding applications such as missile liners, aerospace, and optical molds.
Xu Zhu, Chao Ni, Guilin Chen, Jiang Guo
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Milling Characteristics and Damage Assessment of Ultrasonic Vibration-Assisted End Milling Cf/SiC Composites

Chinese Journal of Mechanical Engineering
Cf/SiC composites are characterized as anisotropic, heterogeneous, brittle, and hard materials. The process of manufacturing Cf/SiC composites using traditional machining techniques is prone to edge chipping damage and tool wear, which makes it difficult
Zhongwang Wang, Zhigang Dong, Yan Bao, Yichuan Ran, Renke Kang   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Dispersion Stability and Tribological Properties of Cold Plasma-Modified h-BN Nanofluid

Nanomaterials
h-BN spherical nanoparticles, known as white graphene, have good anti-wear properties, long service life, chemical inertness, and stability, which provide superior lubricating performance as a solid additive item to nanofluids.
Zhenjing Duan, Ziheng Wang, Yishuai Jia, Shuaishuai Wang, Peng Bian, Ji Tan, Jinlong Song, Xin Liu   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A high-precision polarimeter [PDF]

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2001
We have built a polarimeter in order to measure the electron beam polarization in hall C at JLAB. Using a superconducting solenoid to drive the pure-iron target foil into saturation, and a symmetrical setup to detect the Moller electrons in coincidence, we achieve an accuracy of <1%. This sets a new standard for Moller polarimeters.
Hauger, M., Honegger, A., Jourdan, J., Kubon, G., Petitjean, T., Rohe, D., Sick, I., Warren, G., Wohrle, H., Zhao, J., Ent, R., Mitchell, J., Crabb, D., Tobias, A., Zeier, M., Zihlmann, B.   +15 more
openaire   +2 more sources

Anti-Adhesion Superhydrophobic High-Frequency Electrotome

Applied Sciences
High-frequency electrotome (HFE) encompassing rapid cutting speed, effective hemostasis, and simple operation plays a critical role in the electrosurgical field.
Haodong Fu, Yuheng Li, Jiyu Liu, Hao Liu, Yun Li, Yue Zhao, Defeng Yan, Xin Liu   +7 more
doaj   +1 more source