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High-pressure liquid chromatography of peptides

Journal of Chromatography A, 1977
Peptides varying in size from di- to decapeptide have been subjected to high-pressure liquid chromatography on Phenyl-Corasil, Poragel PN, and Poragel PS under reversed-phase conditions with acetonitrile-water mixtures. It has been found that residual silanol groups in the Phenyl-Corasil and the functional groups in the Poragels significantly influence
J J, Hansen   +4 more
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High frequency dynamics in liquid Cs at high pressure

The Journal of Chemical Physics, 2009
We report on an inelastic x-ray scattering investigation of the high frequency dynamics of liquid cesium at 493 K and 1 GPa, which corresponds to a density 23% higher than that at the room pressure melting point. The analysis of the spectra, performed within the framework of the memory function approach suggests the existence of two different ...
V. GIORDANO, MONACO G
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Liquid densities at high pressures

Fluid Phase Equilibria, 1999
Abstract Aalto et al. recently proposed a model for compressed liquid densities. The model was found more accurate than the Hankinson–Brobst–Thomson (HBT) and Chang–Zhao models. However, the pressure region of the data studied was limited to 200 bar maximum. In this work, the recently developed liquid density model is extended to high pressures.
Mika M Aalto, Kari I Keskinen
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High-back-pressure liquid chromatography

Journal of Chromatography A, 1982
Abstract The retention behaviour of solutes on various stationary phases was studied by micro-high-performance liquid chromatography using liquefied solvents as the mobile phase. An octadecylsilylated stationary phase discriminates between coplanar and non-planar aromatic hydrocarbons in the normal-phase system using isobutane as the mobile phase ...
Toyohide Takeuchi, Daido Ishii
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Liquid-liquid partition coefficients by high-pressure liquid chromatography

Journal of Medicinal Chemistry, 1975
Lipid-water partition values can be rapidly and reliably measured by high-pressure liquid chromatography (HPLC) on bonded octadecylsialne supports. This method has been developed and applied to a family of hypotensive triaminopyrimidine 3-oxides. The measured column retention values for this class of compounds correlate well with the values calculated ...
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High-pressure liquid chromatographic analysis of novobiocin

Journal of Chromatography A, 1974
A high-pressure liquid chromatographic method for the analysis of novobiocin is described. The method uses a 1 -m-long Zipax HCP column with a mobile phase of 15% methanol in 0.02 M phosphate buffer, pH 7.0, at a flow-rate of 0.85 ml/min (68 atm).
K, Tsuji, J H, Robertson
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Laboratory Automation of High‐Pressure Liquid Chromatography

Journal of Pharmaceutical Sciences, 1975
An automated system for high-pressure liquid chromatography was developed. The system is built around commercial modules wherever possible, modified to varying degrees. An automatic sampler, a sample pump, a high-pressure sampling valve, a recorder with an integrator, and a high-pressure liquid chromatograph comprise the commercial instruments. Relays,
W F, Beyer, D D, Gleason
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Thimerosal Determination by High-Pressure Liquid Chromatography

Journal of Pharmaceutical Sciences, 1978
A sensitive and useful high-pressure liquid chromatographic method for the determination of intact thimerosal was developed. This method is extremely fast and reliable, and its inherent specificity makes it a breakthrough over other common wet chemical methods.
R C, Meyer, L B, Cohn
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Effects of high pressure in liquid chromatography

Journal of Chromatography A, 2005
All the experimental parameters that the chromatographers are used to consider as constant (the column length and its diameter, the particle size, the column porosities, the phase ratio, the column hold-up volume, the pressure gradient along the column, the mobile phase density and its viscosity, the diffusion coefficients, the equilibrium constants ...
Martin, Michel, Guiochon, Georges
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Forensic aspects of high-pressure liquid chromatography

Journal of Chromatography A, 1976
This paper reviews the applications of high-pressure liquid chromatography (HPLC) to forensic problems, and discusses some of the developments that have taken place in the use of the technique in the Metropolitan Police Laboratory. Preparation of octadecyltrichlorosilane-modified silica is described and some of the chromatographic characteristics of ...
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