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Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi   +10 more
wiley   +1 more source

Editorial: Advances in food processing and analysis: product quality and green revolution. [PDF]

Front Nutr
Can Karaca A, Cravotto G, Zhao H, Amin T, Rastrelli L.   +4 more
europepmc   +1 more source

From Hemp to CBD Crystals: A Scaled-Up Procedure for the Selective Extraction, Isolation, and Purification of Cannabidiol. [PDF]

ACS Agric Sci Technol
Calmanti R, Selva M, Perosa A.
europepmc   +1 more source

Innovative applications and future perspectives of chromatography-mass spectrometry in drug research. [PDF]

Front Pharmacol
Cai H, Xing X, Su Y, Yang C.
europepmc   +1 more source

The Phytochemical Characterization of a Cili (<i>Rosa roxburghii</i>) Fruit Low-Temperature Extract with Hepatoprotective Effects. [PDF]

Foods
He R, Lian Z, Cheng Z, Liu Y, Peng X, Wang Y, Ma H, Zhou X, Ge F.   +8 more
europepmc   +1 more source

Development of a liquid injection system dedicated to on-line analysis by gas chromatography and its refining applications : study of the behavior and contribution of short monolithic columns in high pressure gas chromatography

, 2016
Adrien Maniquet
openalex   +1 more source

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High Pressure Liquid Chromatography

Journal of Pharmaceutical Sciences, 1973
Abstract Prior to 1967, liquid column chromatography (LCC) separations were not normally carried out in an optimum manner; for this reason, the technique was viewed as slow and inefficient (1–3). Consequently, other techniques such as thin-layer chromatography (TLC) and gas chromatography (GC) found favor.
D.W. Cornish, A.F. Michaelis, R. Vivilecchia   +2 more
openaire   +3 more sources

Effects of high pressure in liquid chromatography

Journal of Chromatography A, 2005
All the experimental parameters that the chromatographers are used to consider as constant (the column length and its diameter, the particle size, the column porosities, the phase ratio, the column hold-up volume, the pressure gradient along the column, the mobile phase density and its viscosity, the diffusion coefficients, the equilibrium constants ...
Georges Guiochon, Georges Guiochon, Michel Martin   +2 more
openaire   +4 more sources

High-pressure liquid chromatography of steroids

Journal of Chromatography A, 1979
After a brief discussion of the merits and limitations of high-pressure liquid chromatography (HPLC) relative to other chromatographic methods, special problems in the application to steroids are discussed. Publications on HPLC of steroids are then discussed under the headings of individual classes, arranged generally in the order of increasing ...
Irving R. Hunter, Erich Heftmann
openaire   +3 more sources