Results 51 to 60 of about 225,502 (309)

On dissolution test for Hypertril tablets using high performance liquid chromatography

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Particular attention is paid to the release of the active ingredients of drugs in the form of tablets. Therefore, we have developed a method for determining the dissolution test, for the original drug Hypertril. The purpose.
L. I. Kucherenko   +4 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Evaluation of homocysteine in blood bank donors [PDF]

open access: yesEinstein (São Paulo), 2005
Objective: To investigate the use of plasma homocysteine levelsin blood bank donors as a risk marker for the development ofcardiovascular diseases in healthy individuals.
Luiz Antonio Rosa
doaj  

Configuration, optimization and evaluation of a novel instrumental platform for automated SPE-LC-MS/MS analysis of drugs in whole blood [PDF]

open access: yes, 2013
The thesis describes the configuration, optimization and evaluation of a novel instrumental platform for fully automated SPE-LC-MS/MS analysis of small molecules, such as drugs, in whole blood. The immunosuppressant Cyclosporine A was chosen as a model
Yu, Qianqian
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

open access: yesAdvanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo   +3 more
wiley   +1 more source

Multimodal Soft Surgical Robots Enabled by Eco‐Degradable, Sterilizable Polymers and Transient Electronics

open access: yesAdvanced Functional Materials, EarlyView.
A compostable PGS soft surgical robot with interchangeable modules integrates transient Mo tactile and Si thermal sensors for dual feedback. The device preserves its function after clinical‐grade sterilization, demonstrates stable actuation and cardiac tissue grasping with real‐time in vivo pulsatile monitoring, and biodegrades post‐use with soil‐safe, 
Minseong Chae   +27 more
wiley   +1 more source

Comparative Study of Continuous Pralidoxime Infusion versus Intermittent Dosing: Application of High-Performance Liquid Chromatography Method on Serum of Organophosphate Poisoned Patients [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2013
Background: The effective therapeutic dose of pralidoxime methylsulphate for organophosphate (OP) poisoning is necessary to be clarified. This study was designed to comparatively assess the blood level of pralidoxime (BPL) and clinical outcomes in OP ...
Girish Thunga   +7 more
doaj  

Integrated Parylene LC-ESI on a Chip [PDF]

open access: yes, 2005
In this thesis, several microfluidic devices will be introduced to demonstrate the integration capability of a multilayer parylene surface micromachining technology.
Xie, Jun
core   +1 more source

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