Results 71 to 80 of about 19,407,241 (210)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Repetition Rate Multiplication Pulsed Laser Source Based on a Microring Resonator

open access: yes, 2017
We demonstrate a stable high-Q microring resonator (MRR)-based pulsed laser source with adjustable repetition rate from 49 to 735 GHz, corresponds to repetition rate multiplication of up to 15X the free spectral range (FSR) of the MRR.
Zhao, Wei   +21 more
core   +1 more source

High-repetition-rate femtosecond-laser micromachining of low-loss optical-lattice-like waveguides in lithium niobate [PDF]

open access: yes, 2018
A series of waveguides were inscribed in lithium niobate by tightly focused femtosecond-laser pulses of 11-MHz repetition rate and 790-nm wavelength. To establish the inscription conditions for optimal low-loss waveguides, within each sample we varied ...
Piromjitpong, Teerawat   +5 more
core   +1 more source

High-power sub-picosecond filamentation at 1.03 {\mu}m with high repetition rates between 10 kHz and 100 kHz

open access: yes, 2023
Filamentation has been extensively explored and is well understood at repetition rates < 1 kHz due to the typical availability of multi-mJ laser systems at moderate average power.
Jean-Pierre Wolf (1505308)   +7 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Diode-Pumped Gigahertz Repetition Rate Femtosecond Cr:Lisaf Laser

open access: yes, 2010
We report a low-cost, 1 GHz repetition-rate, diode-pumped, saturable Bragg reflectors mode-locked Cr:LiSAF laser, which generates nearly transform-limited 103-fs long pulses around 866 nm, with a record high peak power of 1.45 ...
Leslie A. Kolodziejski   +15 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Stability of target irradiation for high-repetition rate direct-drive facilities

open access: yesEPJ Web of Conferences, 2013
The illumination of a spherical target for Inertial Confinement Fusion is studied in the direct-drive approach. Three main sources of laser parameter fluctuation are taken into account, and a statistical analysis of the illumination configuration has ...
Schiavi Angelo   +2 more
doaj   +1 more source

Investigation of high repetition rate optical parametric amplifier. [PDF]

open access: yes, 2018
Investigation of High Repetition Rate Optical Parametric ...
Jurkus, Karolis,
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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