Results 71 to 80 of about 193,097 (307)

Generation of µW level plateau harmonics at high repetition rate

, 2022
S.19374-19383The process of high harmonic generation allows for coherent transfer of infrared laser light to the extreme ultraviolet spectral range opening a variety of applications. The low conversion efficiency of this process calls for optimization or
Rothhardt, J., Demmler, S., Hädrich, S., Carstens, H., Tünnermann, A., Krebs, M., Limpert, J.   +6 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Low energy-density recording with a high-repetition-rate laser beam in gold-nanorod-embedded discs

, 2012
In this paper, we report on the low energy-density recording with a high-repetition-rate femtosecond pulsed beam in homogenous goldnanoroddispersed discs by using low numerical aperture (NA) microoptics.
Jianshe Ma (6443192), Md Azim Ullah (19001054), Xiangping Li (18943936), Xiaojian Hao (13220133), Yahui Su (147015), Min Gu (18943897), Xueming Cheng (19001057)   +6 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

High repetition rate few-cycle OPCPA for generation of isolated attosecond pulses

, 2022
Paper HT3C.1A 20W average power optical parametric amplifier system delivering CEP stable 20µJ, sub 5fs pulses at megahertz repetition rate is presented.
Rothhardt, Jan, Limpert, Jens, Tünnermann, Andreas, Demmler, Stefan, Krebs, Manuel, Hädrich, Steffen   +5 more
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Coherent beam combining strategies for highenergy and high-repetition rate lasers dedicated to inertial nuclear fusion applications

International audienceSpatial Coherent Beam Combining (CBC) strategies are particularly promising for lasers dedicated to nuclear fusion applications in the purpose of developing high-energy and high-repetition-rate lasers. Let us examine their potential
Froidevaux, Marie, Papadopoulos, Dimitris, Druon, Frédéric, de Sousa, Joanna, Lebegue, Pierre, Audebert, Patrick, Meignien, Loïc, Wattellier, Benoit, Badarau, Doina, Ohland, Jonas Benjamin, Rapeneau, Cyril, Doudet, Ivan, Chan, Nolan   +12 more
core   +1 more source