Results 131 to 140 of about 3,665,590 (308)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Piercing Applications among High School Students

open access: yesFlorence Nightingale Journal of Nursing, 2019
Purpose: It is a fashion among teens and can be applied to any part of the body, including genital organs. It is well known that piercing may cause to nerve damage in eyebrow and ear, and diseases like Hepatitis B, C, HIV, Tetanus.
Sevim Savaşer   +3 more
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Mathematical Problem Posing as a Measure of Curricular Effect on Students\u27 Learning [PDF]

open access: yes, 2012
In this study, we used problem posing as a measure of the effect of middle-school curriculum on students\u27 learning in high school. Students who had used a standards-based curriculum in middle school performed equally well or better in high school than
Cai, Jinfa   +5 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pathways to College Preparatory Advanced Academic Offerings in the Anchorage School District [PDF]

open access: yes, 2016
Prepared for: CITC’s Anchorage Realizing Indigenous Student ExcellenceThere are many ways a child in the Anchorage School District (ASD) can access advanced course offerings. To a parent these pathways may seem complex.
Frazier, Rosyland, Hirshberg, Diane
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Digital Technologies and Reading Habits of Students: A Scoping Review

open access: yesOpen Information Science
Students worldwide use digital technologies such as mobile phones, smartphones, computers, tablets, social media, the internet, and digital televisions. This scoping review aims to map the literature on the types of digital technologies and the purposes ...
Saritha   +2 more
doaj   +1 more source

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