Results 101 to 110 of about 6,196,296 (298)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
SensorsAs one of the most promising electronic devices in the post-Moore era, nanoscale vacuum field emission transistors (VFETs) have garnered significant attention due to their unique electron transport mechanism featuring ballistic transport within vacuum ...
Chang Ge +4 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Development of a NIR Iridium(III) Complex-Based Probe for the Selective Detection of Iron(II) Ions
BiosensorsAs a commonly used metal ion, iron(II) (Fe2+) ions pose a potential threat to ecosystems and human health. Therefore, it is particularly important to develop analytical techniques for the rapid and accurate detection of Fe2+ ions.
Wanyi Wang +6 more
doaj +1 more source
Ion-retarding lens improves the abundance sensitivity of tandem mass spectrometers [PDF]
, 1969 Ion-retarding lens which increases the abundance sensitivity of tandem magnetic-analyzer mass spectrometers measures isotopes of low abundance in mass positions adjacent to isotopes of high abundance.
Kaiser, K. A., Stevens, C. M.
core +1 more source
Optomechanical magnetometry with a macroscopic resonator
, 2015 We demonstrate a centimeter-scale optomechanical magnetometer based on a crystalline whispering gallery mode resonator. The large size of the resonator allows high magnetic field sensitivity to be achieved in the hertz to kilohertz frequency range.
Bowen, Warwick P. +7 more
core +1 more source
High-sensitivity photoacoustic leak testing
The Journal of the Acoustical Society of America, 2003 The photoacoustic effect may be exploited for detection and localization of gas leaks on the surface of otherwise sealed components. The technique involves filling the test component with a photoactive tracer gas, and irradiating the component to produce photoacoustic sound from any leak site where a tracer gas cloud forms.
Huang, Eric +3 more
openaire +4 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Cavity-Enhanced Ultrafast Transient Absorption Spectroscopy
, 2015 We present a new technique using a frequency comb laser and optical cavities for performing ultrafast transient absorption spectroscopy with improved sensitivity.
Allison, Thomas K. +2 more
core +1 more source
Interferon Assay of High Sensitivity
Experimental Biology and Medicine, 1976 SummaryA method of aging cells is described which allows for an increase in sensitivity of the assay of interferon. After reaching confluency the cell cultures are aged at 30° for 5 days, the growth medium is replenished, and the cells are incubated for an additional 24 hr at 37° before applying interferon.
E, Lvovsky, H B, Levy
openaire +2 more sources