Results 71 to 80 of about 2,142,116 (352)

Designing a crisis communication plan in the Chinese Ministry of Railways [PDF]

open access: yes, 2013
This project presents a crisis communication plan for the Chinese Ministry of Railways, as Wenzhou high-speed train crash incident is the background.
Xiong, Shengya
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Design and strengthening of dual bio-inspired lattice structures based on additive manufacturing

open access: yesAlexandria Engineering Journal
Lattice structures are widely studied and applied due to their excellent energy absorption capabilities. This study drew inspiration from natural structures and started from the structural form.
Tongyuan Sun   +3 more
doaj   +1 more source

Aeroacoustics in high speed trains

open access: yes, 2022
Este trabajo se centra en el estudio de problemas aeroacústicos en los trenes de alta velocidad. Se han considerado dos escenarios en los que las ondas de presión generadas son críticos para el confort de los pasajeros. Uno es el debido a las ondas de presión que genera el tren cuando entra y sale de un túnel, que a su vez producen saltos de presión de
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Statistical identification of geometric parameters for high speed train catenary [PDF]

open access: yes, 2014
Pantograph/catenary interaction is known to be strongly dependent on the static geometry of the catenary, this research thus seeks to build a statistical model of this geometry.
BALMES, Etienne   +2 more
core   +2 more sources

Modelling extreme wind speeds in the context of risk analysis for high speed trains [PDF]

open access: yes, 2002
For high speed trains there is a potential risk of derailment when driving very fast and being hit by an extraordinary strong gust at the same time. The risk depends on both the wind speed and the angle between train and gust.
Küchenhoff, Helmut, Payer, T.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Development of Domestic High Speed Train Bogie Steel

open access: yesTeshugang, 2022
The material changes and property requirements of domestic railway bogie steel from 1950's ~ 20109 s are summarized. At the same time, the chemical composition design, strength grade and atmospheric corrosion resistance mechanism of steel for cast steel ...
张瑞琦   +5 more
doaj  

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