Results 81 to 90 of about 2,259,182 (352)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Development of Domestic High Speed Train Bogie Steel
Teshugang, 2022 The material changes and property requirements of domestic railway bogie steel from 1950's ~ 20109 s are summarized. At the same time, the chemical composition design, strength grade and atmospheric corrosion resistance mechanism of steel for cast steel ...
张瑞琦 +5 more
doaj
Analysis of ground motion due to moving surface loads induced by high-speed trains [PDF]
, 2007 A three-dimensional time domain boundary element (BE) approach for the analysis of soil vibrations induced by high-speed moving loads is presented in this paper. An attenuation law is included in the formulation.
Domínguez Abascal, José +1 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Advanced Diagnostics of Position Sensors for the Actuation Systems of High-Speed Tilting Trains [PDF]
, 2010 Trains tilting permits a train to travel at a high speed while maintaining an acceptable passenger ride quality with respect to the lateral acceleration, and the consequent lateral force, received by the passengers when the train travels on a curved ...
Jacazio, Giovanni +3 more
core
High Speed Railway Wireless Communications: Efficiency v.s. Fairness
, 2014 High speed railways (HSRs) have been deployed widely all over the world in recent years. Different from traditional cellular communication, its high mobility makes it essential to implement power allocation along the time.
Dong, Yunquan +2 more
core +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Crew Rostering for the High Speed Train [PDF]
At the time of writing we entered the final stage of implementing the crew rostering system Harmony CDR to facilitate the planning of catering crews on board of the Thalys, the High Speed Train connecting Paris, Cologne, Brussels, Amsterdam, and Geneva ...
Lentink, R.M., Odijk, M.A., Rijn, E. van
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Effect of remelting strategy on forming mechanism of selective laser melted AlSi10Mg
Journal of Materials Research and TechnologySelective laser melting (SLM) technology is widely used in various fields for manufacturing high-precision and complex parts. However, SLMed parts still exhibit some microstructural defects.
Deyu Yue +5 more
doaj +1 more source