Results 71 to 80 of about 2,259,182 (352)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Laser additive manufacturing of hierarchical multifunctional chiral metamaterial with distinguished damage-resistance and low-frequency broadband sound-absorption capabilities

Materials & Design
Traditional materials or advanced artificially engineered metamaterials are incapable of effectively addressing the simultaneous challenges of impact energy hazards and low-frequency noise.
Xi Wang, Ruixian Qin, Jiaming Lu, Minghao Huang, Xu Zhang, Bingzhi Chen   +5 more
doaj   +1 more source

Designing a crisis communication plan in the Chinese Ministry of Railways [PDF]

, 2013
This project presents a crisis communication plan for the Chinese Ministry of Railways, as Wenzhou high-speed train crash incident is the background.
Xiong, Shengya
core   +2 more sources

Impact of signal wavelength on the semiconductor opticalamplifier gain uniformity for high speed optical routers employing the segmentation model [PDF]

, 2010
This paper investigates the impact of a train of input Gaussian pulses wavelength on semiconductor optical amplifier (SOA) gain uniformity for high speed applications. In high speed applications, the linear output gain of the input pulses is necessary in
Abd El Aziz, Ahmad, Aly, Moustafa, Chiang, Ming-Feng, Ghassemlooy, Zabih, Ng, Wai Pang, Ngah, Razali   +5 more
core   +2 more sources

Aeroacoustics in high speed trains

, 2022
Este trabajo se centra en el estudio de problemas aeroacústicos en los trenes de alta velocidad. Se han considerado dos escenarios en los que las ondas de presión generadas son críticos para el confort de los pasajeros. Uno es el debido a las ondas de presión que genera el tren cuando entra y sale de un túnel, que a su vez producen saltos de presión de
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Design and strengthening of dual bio-inspired lattice structures based on additive manufacturing

Alexandria Engineering Journal
Lattice structures are widely studied and applied due to their excellent energy absorption capabilities. This study drew inspiration from natural structures and started from the structural form.
Tongyuan Sun, Bingzhi Chen, Deyu Yue, Dongming Li   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

High speed train communications systems using free space optics [PDF]

, 2010
In this work, we propose a broad-band free space optical (FSO) wireless communications system for high-speed trains. The system consists of optical transceivers positioned outside the train and along the railway track.
Ghassemlooy, Zabih, Iaz, M., Le Minh, Hoa, Paudel, Rupak, Rajbhandari, Sujan   +4 more
core