Results 201 to 210 of about 2,048,778 (265)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Effect of Gamification Plus Automated Coaching to Increase Physical Activity Among Patients With Peripheral Artery Disease: The GAMEPAD Randomized Controlled Trial. [PDF]

open access: yesJ Am Heart Assoc
Fanaroff AC   +11 more
europepmc   +1 more source

High-flow PBT resins step up a gear

open access: yesReinforced Plastics, 2007
openaire   +1 more source

Full-body Remodeling With Minimally Invasive Techniques. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Michels P, Araujo R, Michels RTB.
europepmc   +1 more source

Feasibility of a Stepped-Care Intervention for Those at Clinical High Risk for Psychosis in the United States. [PDF]

open access: yesEarly Interv Psychiatry
Shapiro DI   +18 more
europepmc   +1 more source

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