Results 31 to 40 of about 2,756,139 (304)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Virtual Screening in Search for a Chemical Probe for Angiotensin-Converting Enzyme 2 (ACE2)
Molecules, 2021 We elaborate new models for ACE and ACE2 receptors with an excellent prediction power compared to previous models. We propose promising workflows for working with huge compound collections, thereby enabling us to discover optimized protocols for virtual ...
Iryna O. Kravets +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait +23 more
wiley +1 more source
Wildlife Society Bulletin, 2019 Studies of thermal ecology are imperative for understanding habitat use and selection by animals and can inform management decisions for conservation of species and habitat. Chelonian thermal ecology studies have used carapace measurements as proxies for
Adam F. Parlin, Paul J. Schaeffer
doaj +1 more source
Street Outreach Workers: Best Practices and Lessons Learned [PDF]
, 2008 Street outreach workers are an important part of the Senator Charles E. Shannon Jr. Community Safety Initiative (CSI) comprehensive gang and youth violence reduction strategy in Massachusetts1. Street outreach involves the use of individuals to “work the
Bynum, Tim S. +4 more
core +1 more source
Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis
Arthritis Care &Research, Accepted Article.Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham +14 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni +7 more
wiley +1 more source
Clinical, histological, and serological predictors of renal function loss in lupus nephritis.
Arthritis Care &Research, Accepted Article.Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang +21 more
wiley +1 more source
Calorie labelling on the high street
BMJ, 2011 A step forward, but changes in food supply must follow In the linked cross sectional surveys (doi: 10.1136/bmj.d4464), Dumanovsky and colleagues assess the effect of a menu labelling regulation on calories (1 kcal=4.18 kJ) per purchase at fast food chains in New York City.1 The need to find new approaches to stimulate dietary change is self evident ...
openaire +1 more source
In Situ Amine Formation to Modulate MOF‐Derived PdIn N‐Doped Carbon Catalysts
Advanced Materials, EarlyView.An amine‐assisted approach converts PdIn‐MOF into PdIn intermetallic nanoparticles embedded in N‐doped carbon. In situ‐generated amines trigger early Pd nucleation, producing smaller PdIn domains than direct pyrolysis. Amine sterics and basicity tune composition and particle size, while solvent and amine co‐determine textural features.
Gonzalo Egea +9 more
wiley +1 more source