Results 51 to 60 of about 4,094,018 (318)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Static and Dynamic Thermophysical Property Measurements at High Temperature
, 2003 In view of the importance of generating reliable and self consistent thermophysical data, efforts have been made in the Division of Metallurgy, Royal Institute of Technology, Stockholm to measure the viscosities and thermal diffusivities of ...
E. Kapilashrami, +7 more
core +1 more source
, 2023 Nano/micro-electromechanical (NEM/MEM) contact switches have great potential as energy-efficient and high-temperature-operable computing units to surmount those limitations of transistors.
Jongbaeg Kim +9 more
core +1 more source
Micromachines, 2023 Low-temperature (350 °C) vitrification in a KNO3-NaNO3-KHSO4-NH4H2PO4 system, containing various additives to improve the chemical durability of the obtained material, was investigated.
Alexander Gorokhovsky +8 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modeling High-Temperature Superconductivity: Correspondence at Bay? [PDF]
, 2007 How does a predecessor theory relate to its successor? According to Heinz Post's General Correspondence Principle, the successor theory has to account for the empirical success of its predecessor.
Hartmann, Stephan, Stephan Hartmann
core +1 more source
Thermodynamic Calculation of Equilibrium Phases of K488 Alloy
Journal of Aeronautical Materials, 2018 The influence of equilibrium and alloy elements on the precipitation phases of K488 alloy was calculated and experimental analyzed by using Thermo-Calc thermodynamic calculation software. The results of calculation and experiment are shown that the alloy
MENG Fanguo +4 more
doaj +1 more source
Creep Rupture Behavior in Dissimilar Weldment between FB2 and 30Cr1Mo1V Heat-Resistant Steel
International Journal of Photoenergy, 2021 Creep rupture behavior of dissimilar weldments between FB2 and 30Cr1Mo1V heat-resistant steel by multipass welding at 783 K (510°C) under different stresses (260 to 420 MPa) was researched.
Jiankun Xiong +8 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source