Results 81 to 90 of about 7,910,907 (308)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
High-temperature electric stator [PDF]
, 1970 Thermal vacuum tests are conducted on high-temperature stator without a rotor. Electrical characteristics remained satisfactory during tests, insulation improved slightly, and conductor resistance remained constant.
Kueser, P., Lindberg, R. A.
core +1 more source
, 2015 High-temperature electrolysis (also called steam electrolysis) is the water electrolysis at temperatures that ranged between 700 and 1,000 °C in which electrical energy is the driving force of water splitting to produce oxygen (O2) and hydrogen (H2). The core of an electrolysis unit is an electrochemical cell, which is filled with pure water and has ...
openaire +3 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
High temperature acoustic levitator [PDF]
, 1984 A system is described for acoustically levitating an object within a portion of a chamber that is heated to a high temperature, while a driver at the opposite end of the chamber is maintained at a relatively low temperature.
Barmatz, M. B.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Low-temperature corrosion in large-scale biomass boilers
npj Materials DegradationThe shift toward biomass fuels for heat and power generation has introduced a range of new challenges for power plant technology, in particular large-scale boilers.
Farzad Jafarihonar +3 more
doaj +1 more source
Chimica Techno ActaThe paper presents the results of the study on an electrochemical solid electrolyte sensor with a diffusion barrier for simultaneous measurements of carbon (II) oxide and moisture concentrations in the initial gaseous mixture for the carbon oxide ...
Anatoly S. Kalyakin +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source