Results 81 to 90 of about 14,831,642 (287)

High-throughput phenotyping using digital and hyperspectral imaging-derived biomarkers for genotypic nitrogen response

, 2021
A correction has been published: Journal of Experimental Botany, Volume 72, Issue 13, 22 June 2021, Page 5093, https://doi.org/10.1093/jxb/erab126Abstract: The development of crop varieties with higher nitrogen use efficiency is crucial for sustainable ...
Bikram P Banerjee (11173710), German Spangenberg (9477560), Surya Kant (10798998), Sameer Joshi (7514300), Emily Thoday-Kennedy (7820975), Josquin Tibbits (3913912), Raj K Pasam (11173713), Matthew Hayden (9481265)   +7 more
core   +1 more source

Can High Throughput Phenotyping Help Food Security in the Mediterranean Area?

Frontiers in Plant Science, 2019
According to the IPCC 2014 report the Mediterranean region will be affected by strong climatic changes, both in terms of average temperature and of precipitations regime.
Donatella Danzi, Nunzio Briglia, Angelo Petrozza, Stephan Summerer, Giovanni Povero, Alberto Stivaletta, Francesco Cellini, Domenico Pignone, Domenico Pignone, Domenico De Paola, Michela Janni, Michela Janni   +11 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

EuroPhenome: a repository for high-throughput mouse phenotyping data [PDF]

Nucleic Acids Research, 2009
The broad aim of biomedical science in the postgenomic era is to link genomic and phenotype information to allow deeper understanding of the processes leading from genomic changes to altered phenotype and disease. The EuroPhenome project (http://www.EuroPhenome.org) is a comprehensive resource for raw and annotated high-throughput phenotyping data ...
Morgan, Hugh, Beck, Tim, Blake, Andrew, Gates, Hilary, Adams, Niels, Debouzy, Guillaume, Leblanc, Sophie, Lengger, Christoph, Maier, Holger, Melvin, David, Meziane, Hamid, Richardson, Dave, Wells, Sara, White, Jacqui, Wood, Joe, De Angelis, Martin Hrabé, Brown, Steve D M, Hancock, John M., Mallon, Ann Marie, Neyses, Ludwig, Cartwright, Elizabeth, Prehar, Sukhpal, Zi, Min, Muller, Werner   +23 more
openaire   +5 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

High-Throughput phenotyping for leaf-to-fruit ratio characterization in grapevine and its impact on sugar accumulation

International audienceControlling sugar levels in grapes is a major challenge for adapting grapevine cultivation to climate change. Sugar levels, which vary widely between varieties, are influenced by factors such as the onset of riepening and the leaf ...
Reibel, Nicolas, Ben Hamden, Jacem, Duchêne, Eric, Ley, Lionel, Dumas, Vincent   +4 more
core   +3 more sources

Picturing the future of food

Plant Phenome Journal, 2021
High‐throughput phenotyping (HTP) has emerged as one of the most exciting and rapidly evolving spaces within plant science. The successful application of phenotyping technologies will facilitate increases in agricultural productivity.
Anna L. Casto, Haley Schuhl, Jose C. Tovar, Qi Wang, Rebecca S. Bart, Noah Fahlgren, Malia A. Gehan   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source