Results 111 to 120 of about 1,871,500 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A high resolution full-field range imaging system for robotic devices

, 2005
There has been considerable effort by many researchers to develop a high resolution full-field range imaging system. Traditionally these systems rely on a homodyne technique that modulates the illumination source and shutter speed at some high frequency.
Dorrington, Adrian A., Payne, Andrew D., Carnegie, Dale A., Cree, Michael J.   +3 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Mathematical Model for Hydropower Plant (HPP) Electricity Forecasting with High Time Resolution

Energies
Forecasting hydropower plant power production is a great challenge in the context of maintaining power system stability, reliability and efficiency, especially in an age with variable renewable energy sources when demand for electricity is steadily ...
Viktor Alexiev, Boris Marinov, Vasil Shterev, Rad Stanev, Bozhidar Bozhilov   +4 more
doaj   +1 more source

Air pollutant variations in Suzhou during the 2019 novel coronavirus (COVID-19) lockdown of 2020: High time-resolution measurements of aerosol chemical compositions and source apportionment. [PDF]

Environ Pollut, 2021
Wang H, Miao Q, Shen L, Yang Q, Wu Y, Wei H.   +5 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Mining change patterns in time series high-resolution SAR images

The Journal of Engineering, 2019
Here, the authors use the K-Shape algorithm, which is based on a z-normalised version of cross-correlation distance measure, to extract change patterns from time series synthetic aperture radar (SAR) images.
Dong Peng, Ting Pan, Wen Yang, Heng-Chao Li, Mingsheng Liao   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Nanometric depth resolution from multi-focal images in microscopy [PDF]

, 2011
We describe a method for tracking the position of small features in three dimensions from images recorded on a standard microscope with an inexpensive attachment between the microscope and the camera.
Dalgarno, Heather I. C., Dalgarno, Heather I.C., Dada, Adetunmise C., Greenaway, AH, Parton, Richard M., Dalgarno, H. I C, Dada, Adetunmise C, Towers, Catherine E., Gavin J. Gibson, Dalgarno, Paul A., Gibson, GJ, Paul A. Dalgarno, Adetunmise C. Dada, Richard J. Warburton, Parton, Richard M, Alan H. Greenaway, Gibson, Gavin J, Gibson, Gavin J., Dalgarno, Paul A, Warburton, RJ, Catherine E. Towers, Dalgarno, HI, Ilan Davis, Greenaway, Alan H, Davis, Ilan, Greenaway, Alan H., Parton, RM, Towers, Catherine E, Dada, AC, Dalgarno, Heather I C, Heather I. C. Dalgarno, Warburton, Richard J., Warburton, Richard J, Richard M. Parton, Dalgarno, PA, Davis, I, Towers, CE, Dalgarno, Paul A.; id_orcid   +37 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source