Results 161 to 170 of about 1,871,500 (313)

Examining spatiotemporal variability of urban particulate matter and application of high-time resolution data from a network of low-cost air pollution sensors. [PDF]

Atmos Environ (1994), 2019
Feinberg SN, Williams R, Hagler G, Low J, Smith L, Brown R, Garver D, Davis M, Morton M, Schaefer J, Campbell J.   +10 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Time to go wild: How to conceptualize and measure process dynamics in real teams with high-resolution

, 2019
Team processes are interdependent activities among team members that transform inputs into outputs, vary over time, and are critical for team effectiveness.
SK Parker (14653511), F Klonek (14617820), FH Gerpott (14653508), N Lehmann-Willenbrock (14617823)   +3 more
core   +1 more source

Application of calibrated forceps for assessing mechanical nociception with high time resolution in mice. [PDF]

PLoS One, 2017
Kashiwadani H, Kanmura Y, Kuwaki T.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Enhanced Contention Resolution Aloha - ECRA

, 2013
Random Access (RA) Medium Access (MAC) protocols are simple and effective when the nature of the traffic is unpredictable and random. In the following paper, a novel RA protocol called Enhanced Contention Resolution ALOHA (ECRA) is presented.
Kissling, Christian, Clazzer, Federico
core  

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Extracting fluorescent reporter time courses of cell lineages from high-throughput microscopy at low temporal resolution [PDF]

Live Cell Imaging and High Throughput Screening are rapidly evolving techniques and have found many applications in recent years. Modern microscopy enables the visualisation of internal changes in the cell through the use of fluorescently tagged ...
Downey, Mike J.
core  

Widefield Two-Photon Excitation without Scanning: Live Cell Microscopy with High Time Resolution and Low Photo-Bleaching. [PDF]

PLoS One, 2016
Amor R, McDonald A, Trägårdh J, Robb G, Wilson L, Abdul Rahman NZ, Dempster J, Amos WB, Bushell TJ, McConnell G.   +9 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source