Results 51 to 60 of about 1,871,500 (313)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Fully discrete high resolution schemes for systems of conservation laws [PDF]
, 1994 Effective and robust high resolution schemes are of vital importance for simulation of viscous and inviscid flows. Since second-order high resolution schemes in practice are inadquate for many applications, large efforts have been put towards ...
Shi, Jian
core
Studies of Chamber Organic Aerosol using an Aerodyne High-Resolution Time-of-Flight Aerosol Mass Spectrometer [PDF]
, 2011 Secondary organic aerosol (SOA) contributes a substantial fraction to total ambient particulate mass. SOA is a complex mixture of different organic species formed via many gas- and particle-phase reaction pathways. The Aerodyne aerosol mass spectrometer (
Chhabra, Puneet Singh
core +1 more source
A minute-resolution downscaling algorithm for high-resolution global irradiance time series
Solar Energy AdvancesNumerous studies have demonstrated the significant impact of the resolution of solar irradiation data on the outcomes of hourly production models. Accurate integration of photovoltaic (PV) systems sometimes demands a high-resolution global horizontal ...
Diamantis Almpantis +2 more
doaj +1 more source
Estimation of grassland use intensities based on high spatial resolution LAI time series [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015 The identification and surveillance of agricultural management and the measurement of biophysical canopy parameters in grasslands is relevant for environmental protection as well as for political and economic reasons, as proper grassland management is ...
S. Asam, D. Klein, S. Dech
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Spatially detailed retrievals of spring phenology from single-season high-resolution image time series [PDF]
, 2017 Vegetation indices derived from satellite image time series have been extensively used to estimate the timing of phenological events like season onset.
Meroni, Michele +34 more
core +1 more source
High resolution X-ray Timing from a LOFT
, 2010 LOFT (Large area Observatory For X-ray Timing) is an innovative mission concept for a next generation of X-ray timing experiments. Recent developments in the field of Silicon detectors allow to design a realistic observatory devoted to X-ray ...
N. Zampa +25 more
core +2 more sources