Results 101 to 110 of about 23,147,281 (293)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Multiterminal High‐Voltage Direct Current Projects: A Comprehensive Assessment and Future Prospects

open access: yesHigh Voltage
Multiterminal high‐voltage direct current (MT‐HVDC) systems are an important part of modern power systems, addressing the need for bulk power delivery and efficient renewable energy integration.
Mohammad Hossein Mousavi   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Development of a sensor for corona current measurement under high-voltage direct-current transmission lines

open access: yesInternational Journal of Distributed Sensor Networks, 2016
A sensor-based distributed measurement system is designed for collecting and monitoring the corona current under the extremely high-voltage direct-current transmission lines.
Encheng Xin, Haiwen Yuan
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Walrus optimizer-based optimal fractional order PID control for performance enhancement of offshore wind farms

open access: yesScientific Reports
Offshore wind farms (OWFs) play a crucial role in producing renewable energy in modern electrical power systems. However, to ensure that these facilities operate smoothly, they require robust control systems.
Mohamed A. M. Shaheen   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Motion studies of high current arcs using an optical fiber array based imaging system

open access: yes, 2009
This paper presents an integrated portable measurement system for the study of high speed and high temperature unsteady plasma flows such as those found in the vicinity of high current switching arcs.
Sharkh, S.M.   +10 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Method for calculating corona inception voltage of ultra‐high‐voltage direct current transmission lines with frequency‐domain characteristics of corona current

open access: yesIET Generation, Transmission & Distribution, 2017
Corona inception voltage is of great significance for the design of ultra‐high‐voltage direct current transmission lines. In this study, based on the change rule of frequency‐domain characteristics of corona current, a new method for calculating corona ...
Yingyi Liu   +4 more
doaj   +1 more source

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