Results 121 to 130 of about 794,089 (300)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Method for calculating corona inception voltage of ultra‐high‐voltage direct current transmission lines with frequency‐domain characteristics of corona current

open access: yesIET Generation, Transmission & Distribution, 2017
Corona inception voltage is of great significance for the design of ultra‐high‐voltage direct current transmission lines. In this study, based on the change rule of frequency‐domain characteristics of corona current, a new method for calculating corona ...
Yingyi Liu   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Study of switching transients in high frequency converters [PDF]

open access: yes
As the semiconductor technologies progress rapidly, the power densities and switching frequencies of many power devices are improved. With the existing technology, high frequency power systems become possible. Use of such a system is advantageous in many
Elbuluk, Malik E.   +2 more
core   +1 more source

Students' Understanding of Direct Current Resistive Electrical Circuits

open access: yes, 2003
Research has shown that both high school and university students' reasoning patterns regarding direct current resistive electric circuits often differ from the currently accepted explanations.
Beichner, Robert J.   +1 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Polytopic Lyapunov Function-Based Hybrid Switching Control Strategy for High Voltage Direct Current Networks

open access: yesIEEE Open Access Journal of Power and Energy
The increased use of High-Voltage Direct Current transmission networks requires appropriate control strategies for the converter stations, which are crucial to ensure uninterrupted energy supply.
Rohan Kamat Tarcar   +2 more
doaj   +1 more source

High Input Impedance Voltage-Mode Universal Biquadratic Filters With Three Inputs Using Three CCs and Grounding Capacitors [PDF]

open access: yes, 2012
Two current conveyors (CCs) based high input impedance voltage-mode universal biquadratic filters each with three input terminals and one output terminal are presented. The first circuit is composed of three differential voltage current conveyors (DVCCs),
Horng, J. W., Hsu, C. H., Tseng, C. Y.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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