Results 211 to 220 of about 1,816,478 (387)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Design of a high voltage gain converter using coupled inductor with reduced voltage stress for photovoltaic energy based systems. [PDF]

Sci Rep
Hashemzadeh SM, Hosseini SH.
europepmc   +1 more source

Switched capacitor high voltage gain DC-DC Converters for hydrogen vehicles: a detailed comprehensive analysis

Anusha Gaddala, A. V. V. Sudhakar, Shaik. Rafikiran, Ram Deshmukh, CH Hussaian Basha   +4 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A novel ZVS full-bridge cascaded step-up DC-DC converter with resonant auxiliary circuit for high voltage-gain applications. [PDF]

PLoS One
Hossain MZ, Selvaraj JA, Rahim NA.
europepmc   +1 more source

High Voltage Gain WSe₂ Complementary Compact Inverter With Buried Gate for Local Doping

, 2020
Da Wan, Bei Jiang, Hao Huang, Chen Chen, Ablat Abliz, Cong Ye, Xingqiang Liu, Xuming Zou, Guoli Li, Denis Flandre, Lei Liao   +10 more
openalex   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

A novel on high voltage gain boost converter with cuckoo search optimization based MPPTController for solar PV system. [PDF]

Sci Rep
Mariprasath T, Basha CHH, Khan B, Ali A.
europepmc   +1 more source

Exploiting Negative Differential Resistance in Monolayer Graphene FETs for High Voltage Gains [PDF]

, 2014
Roberto Grassi, Antonio Gnudi, Valerio Di Lecce, Elena Gnani, Susanna Reggiani, Giorgio Baccarani   +5 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source