Results 81 to 90 of about 500,458 (304)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Bottlenecks reduction using superconductors in high voltage transmission lines

open access: yesMATEC Web of Conferences, 2016
Energy flow bottlenecks in high voltage transmission lines known as congestions are one of the challenges facing power utilities in fast developing countries.
Daloub Labib   +3 more
doaj   +1 more source

Electrical power infrastructure for modern rolling stock with regard to the railway in Poland [PDF]

open access: yesArchives of Transport, 2017
Implementing high-speed trains on Polish railway lines requires a new approach to the issue of power and energy supply via a 3 kV DC power system. Due to the control systems used, modern rolling stock equipped with asynchronous drive allows maintaining a
Adam Szeląg
doaj   +1 more source

Influence of very high voltage and extra high voltage AC power lines on pipelines [PDF]

open access: yes, 2017
Cieľom tejto bakalárskej práce je popísať problematiku indukovaného napätia a výpočet indukovaného napätia na jednotlivých úsekoch plynovodu. V teoretickej časti sa budeme zaoberať popisom jednotlivých vlivov pôsobiacich na potrubia pod vlivom napätia s ...
Roman, Denis
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

SYNTHESIS OF AN ACTIVE SHIELDING SYSTEM OF THE MAGNETIC FIELD OF POWER LINES BASED ON MULTIOBJECTIVE OPTIMIZATION

open access: yesElectrical engineering & Electromechanics, 2016
Purpose. The synthesis of the active shielding systems by technogenic magnetic field generated by the different types of high voltage power lines in a given region of space using various cables of controlled magnetic field sources. Methodology.
B. I. Kuznetsov   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Voltage and current spectra for matrix power converters [PDF]

open access: yes, 2009
Matrix power converters are used for transforming one alternating-current power supply to another, with different peak voltage and frequency. There are three input lines, with sinusoidally varying voltages which are 120◦ out of phase one from another ...
Bowes S. R.   +2 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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