Results 51 to 60 of about 23,194,386 (293)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Study of Ethiopian genetically modified and organic cotton fiber quality compared with conventional cotton

Cogent Food & Agriculture
In Ethiopia, investigation of fiber quality and commercialization is limited to conventional cotton and there is no fiber property analysis for Organic and genetically modified cotton.
Chirato Godana Korra, Kura Alemayehu Beyene, Tiliksew Addis Desta   +2 more
doaj   +1 more source

MATHEMATICS CREATIVE THINKING SKILLS INSTRUMENT TO SOLVE CUBE AND RECTANGULAR PRISM VOLUME PROBLEMS FOR ELEMENTARY SCHOOL STUDENTS

MaPan: Jurnal Matematika dan Pembelajaran, 2021
Mathematical creative thinking skills can help students solve mathematical problems with diverse, unique, and detailed solutions and strategies. This study aims to produce an instrument capable of obtaining information about students' mathematical ...
Aan Yuliyanto, Turmudi Turmudi, Ernawulan Syaodih, Arie Dharmawan, Cahya Karisma Pertiwi, Idat Muqodas, Dadan Rusdiana Saputra   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Improving instrument recognition in polyphonic music through system integration [PDF]

, 2014
A method is proposed for instrument recognition in polyphonic music which combines two independent detector systems. A polyphonic musical instrument recognition system using a missing feature approach and an automatic music transcription system based on ...
Plumbley, MD, Mark D. Plumbley, Benetos, E., Giannoulis, D, Anssi Klapuri, Emmanouil Benetos, Klapuri, A., Benetos, E, Dimitrios Giannoulis, Klapuri, A, Plumbley, M. D., IEEE, Giannoulis, D.   +12 more
core   +1 more source

Reliability analysis of component strain and volume strain at Dongping seismic station and comparison of influence of special events

地震科学进展, 2023
In this paper, the reliability analysis of the YRY-4 borehole component strain observation data at Dongping seismic station is carried out through the four-component self-check and the relative calibration internal accuracy analysis.
Fangfang Xu, Chenglin Zhu, Yuan Jia, Shuangling Lu   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Estimating global oilfield-specific flaring with uncertainty using a detailed geographic database of oil and gas fields

Environmental Research Letters, 2021
Associated gas flaring during crude oil production is an important contributor to global warming. Satellite technology has made global flaring monitoring possible with high spatial resolution.
Zhan Zhang, Evan D Sherwin, Adam R Brandt   +2 more
doaj   +1 more source