Results 61 to 70 of about 23,194,386 (293)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Interfacing complex laboratory instruments during a change to epic beaker

open access: yesJournal of Pathology Informatics, 2018
Background: Implementing a laboratory-developed test sometimes requires incorporating an unconventional device into the laboratory information system (LIS) and customizing an interface to reduce transcription error and improve turnaround time.
Gregory David Scott   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Self-heating probe instrument and method for measuring high temperature melting volume change rate of material

open access: yesChinese Journal of Mechanical Engineering, 2013
The castings defects are affected by the melting volume change rate of material. The change rate has an important effect on running safety of the high temperature thermal storage chamber, too. But the characteristics of existing measuring installations are complex structure, troublesome operation and low precision.
Junwei Wang   +3 more
openaire   +1 more source

Elimination of Instrument-Driven Reflex Manual Differential Leukocyte Counts [PDF]

open access: yesAmerican Journal of Clinical Pathology, 2003
Automated peripheral blood leukocyte differential counts (LDCs) are widely accepted in routine practice. However, many laboratories still reflexively perform manual LDCs based solely on abnormal automated results or instrument "flags," before any manual triage step.
Kay L, Lantis   +4 more
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

CO measurements from the ACE-FTS satellite instrument: data analysis and validation using ground-based, airborne and spaceborne observations [PDF]

open access: yes, 2007
The Atmospheric Chemistry Experiment (ACE) mission was launched in August 2003 to sound the atmosphere by solar occultation. Carbon monoxide (CO), a good tracer of pollution plumes and atmospheric dynamics, is one of the key species provided by the ...
Emmons, Louisa   +185 more
core   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

In-flight Monitoring of TerraSAR-X Radar Instrument Stability [PDF]

open access: yes, 2007
For calibrating and monitoring the radiometric stability, the radar instrument of TerraSAR-X hosts a passive calibration network coupling into an additional port of the T/R modules. Three different types of calibration pulses are applied, whereby sets of
Schwerdt, Marco   +2 more
core  

Implementation of Vibrancy Awaking Pressure Measuring Instrument for Single Hydraulic Prop

open access: yesJournal of Measurement Science and Instrumentation, 2011
An instrument awakened by means of vibration for single hydraulic prop pressure measuring is described in this paper.The principle and implementation of this method are introduced in detail.The instrument uses the high-performance single chip C8051F310 ...
Feng-long ZHENG   +4 more
doaj  

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