Results 111 to 120 of about 1,739,474 (329)
Higher order topological derivatives in elasticity
, 2010 The topological derivative provides the variation of a response functional when an infinitesimal hole of a particular shape is introduced into the domain.
Mariana Silva +5 more
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Validity of feedback controls depending on higher order derivatives
, 1993 Dynamical systems with feedback controls depending on higher order derivatives are considered. It is demonstrated that, with proper interpretation, such systems present no contradictions with the principle that any event is a consequence of a cause ...
Galperin, E.A.
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A New Composite Dissimilarity Measure for Planar Curves Based on Higher-Order Derivatives
MathematicsWith the rapid development of information technology, the problem of curve matching has appeared in many application domains, including sequence analysis, signals processing, speech recognition, etc.
Yupeng Wang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Best constants for Sobolev inequalities for higher order fractional derivatives
, 2004 We obtain sharp constants for Sobolev inequalities for higher order fractional derivatives. As an application, we give a new proof of a theorem of W.
Cotsiolis, Athanase +1 more
core +1 more source
Abstract and Applied Analysis, 2013 In this paper, conservation laws for the (2+1)-dimensional ANNV equation and KP-BBM equation with higher-order mixed derivatives are studied. Due to the existence of higher-order mixed derivatives, Ibragimov’s “new conservation theorem” cannot be applied
Li-hua Zhang
doaj +1 more source
Ball Convergence of an Efficient Eighth Order Iterative Method Under Weak Conditions
Mathematics, 2018 The convergence order of numerous iterative methods is obtained using derivatives of a higher order, although these derivatives are not involved in the methods.
Janak Raj Sharma +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Incorporating derivative order flow in foreign exchange microstructure theory
, 2008 Includes abstract.Includes bibliographical references (p. 36-38).This paper justifies the claim that orders on exchange rate derivatives, including forwards, swaps and options, have a place in exchange rate determination.
Condon, Kieran
core