Results 71 to 80 of about 16,791 (265)

Nonresonance impulsive higher order functional nonconvex-valued differential inclusions

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2002
In this paper, the authors investigate the existence of solutions for nonresonance impulsive higher order functional differential inclusions in Banach spaces with nonconvex valued right hand side. They present two results.
Mouffak Benchohra   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Off-shell single-top-quark production in the Standard Model Effective Field Theory

open access: yesJournal of High Energy Physics, 2019
We present a fully differential and spin-dependent t-channel single-top-quark calculation at next-to-leading order (NLO) in QCD including off-shell effects by using the complex mass scheme in the Standard Model (SM) and in the Standard Model Effective ...
Tobias Neumann, Zack Sullivan
doaj   +1 more source

Higher order differential operators on graphs

open access: yes, 2020
This thesis consists of two papers, enumerated by Roman numerals. The main focus is on the spectral theory of -Laplacians. Here, an -Laplacian, for integer , refers to a metric graph equipped with a differential operator whose differential expression is the -th derivative.
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Higher order differential operators on projective modules

open access: yes, 2011
Corollaries 3.3, 3.4 and 3.5 removed because of an error. June 2022: Some changes made to the introduction. Some references and examples added. July 2022: Extended introduction. August 2022: Minor revision.
openaire   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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