Results 121 to 130 of about 4,518,702 (324)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

A Tale of Many Canadas: Associations of Ancestry With Juvenile Idiopathic Arthritis Categories and Disease Severity at Presentation to Care

ACR Open Rheumatology
Objective To assess associations of ancestry with juvenile idiopathic arthritis (JIA) categories and clinical Juvenile Arthritis Disease Activity Scores (cJADAS10) at presentation to pediatric rheumatology care in a multicultural country with universal ...
Stephanie K. A. Wong, Lori B. Tucker, Kristin Houghton, David A. Cabral, Mercedes Chan, Kimberly A. Morishita, Rae S. M. Yeung, Kiem Oen, Ciaran M. Duffy, Roberta A. Berard, Gaëlle Chédeville, Thomas Loughin, Jaime Guzman, for the ReACCh‐Out investigators   +13 more
doaj   +1 more source

The role of food categories in shaping socioeconomic impacts on the water footprint of household food waste

Cleaner and Responsible Consumption
Household food waste poses a serious threat to planetary boundaries, particularly regarding water use, since it translates directly into unnecessary consumption of virtual water, contributing to freshwater depletion and threatening water security in ...
Pilar Gracia-de-Rentería, Hugo Ferrer-Pérez   +1 more
doaj   +1 more source

Higher K-theory of polynomial categories [PDF]

, 2011
Satoshi Mochizuki, Akiyoshi Sannai
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Lifetime effects and cost-effectiveness of standard and higher-intensity statin therapy across population categories in the UK: a microsimulation modelling studyResearch in context

The Lancet Regional Health. Europe
Summary: Background: Cardiovascular disease incidence and mortality have declined across developed economies and granular up-to-date cost-effectiveness evidence is required for treatments targeting large populations.
Borislava Mihaylova, Runguo Wu, Junwen Zhou, Claire Williams, Iryna Schlackow, Jonathan Emberson, Christina Reith, Anthony Keech, John Robson, Richard Parnell, Jane Armitage, Alastair Gray, John Simes, Colin Baigent   +13 more
doaj   +1 more source

SCIENTIFIC CATEGORY AND SOCIO-ECONOMIC ESSENCE OF “QUALITY OF HIGHER EDUCATION”

, 2023
Abdurahim Vakhabov, Marufkhan Khujakhanov   +1 more
openalex   +2 more sources

Maps of degree one, relative LS category and higher topological complexities [PDF]

, 2020
Yuli B. Rudyak, Soumen Sarkar
openalex   +1 more source

Rewriting in higher dimensional linear categories and application to the affine oriented Brauer category

, 2016
In this paper, we introduce a rewriting theory of linear monoidal categories. Those categories are a particular case of what we will define as linear (n, p)-categories.
Alleaume, Clément
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source