Results 121 to 130 of about 3,003,635 (305)
Experimental and optimization study on time and pressure effects in a vortex refrigeration unit
Discover Applied SciencesThis work focusses on the design, fabrication, experimentation, and optimization of a vortex refrigeration system, emphasizing the effects of inlet pressure, valve position, and operating duration on system performance.
Sampath Suranjan Salins +6 more
doaj +1 more source
Diversity of structures for higher education
, 2020 This book presents many of the papers that were delivered at a workshop on Universities, Colleges, and Others: Diversity of Structures for Higher Education, held at CEPES in 1993 in Bucharest, Romania. Among the compiled themes are as follows: 1) History,
UNESCO European Centre for Higher Education
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Higher education service learning with First Peoples of Australia [PDF]
, 2015 Australian higher education institutions face increasing pressure to institute Aboriginal and Torres Strait Islander culture at every level of activity.
Sunderland, Naomi +7 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
The Condition of Higher Education in New Mexico 2005-2006
, 2019 The Condition of Higher Education in New Mexico 2005-2006 reports on data collected by the New Mexico Higher Education Department as part of its Data Editing and Reporting (DEAR) system.
New Mexico Higher Education Department
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