Results 131 to 140 of about 15,964,509 (348)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Are you happy now? A fictional narrative exploration of educator experiences in higher education during the time of #FeesMustFall [PDF]
Marguerite Müller
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Editorial Team Tuning Journal for Higher Education
doaj +4 more sources
Education Pays: The Benefits of Higher Education for Individuals and Society [PDF]
Sandy Baum, Jennifer Ma, Kathleen Payea
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Challenging Deficit Constructions of the International Student Category in Canadian Higher Education
Victoria Surtees
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The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Spatial epidemiology of dengue and chikungunya in Karnataka using GIS-based analysis
Background Dengue and chikungunya are major vector-borne diseases with significant public health concerns. Understanding their spatial distribution is crucial for effective disease control and prevention strategies.
Prathiksha Prakash Nayak +3 more
doaj +1 more source
Who is responsible for E-Learning Success in Higher Education? A Stakeholders' Analysis [PDF]
Nicole L. Wagner +2 more
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