Results 71 to 80 of about 3,003,635 (305)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Proprietary credit transferability strategy plan : a report to the Governor, President and Minority Leader of the Senate, and Speaker and Minority Leader of the House of Representatives in Response to HB 49 and Ohio Revised Code 3333.166

open access: yes, 2018
"December 31, 2018."; Includes bibliographical referencesIntroduction and charge of committee -- Principles for designing a strategy plan -- Key issues discussed -- Strategy plan -- ConclusionOhio Revised Code section 3333.166 charged the Chancellor of ...
Ohio. Department of Higher Education.
core  

HIGHER MEDICAL EDUCATION. [PDF]

open access: yesJournal of the American Medical Association, 1891
The promotion of all efforts to advance and raise the standard of medical education is always a vital subject with those who have at heart the best interests of our profession. And it is with a sense of gratification that we note from year to year a visible improvement in the standard adopted and approved by the leading educators of our country.
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

State boards of higher education /

open access: yes, 1976
Bibliogr
ERIC Clearinghouse on Higher Education   +1 more
core  

A more holistic form of higher education: The real potential of Work Based Learning [PDF]

open access: yes, 2002
This is the author's pre-print of an article that appeared in Widening Participation and Lifelong Learning. Its reproduction is with the kind permission of Open University Press.This article takes, as its starting-point, the concept of ‘ critical being ...
Major, David
core  

Higher education: Distance education and mercantilization of higher education

open access: yes, 2019
Este artigo objetiva comparar, no nível do ensino superior, a educação a distância ministrada pelos conglomerados educacionais com a EaD veiculada, sobretudo, pelas universidades públicas, PUCs, e instituições ligadas à Rede Federal de Educação Profissional Científica e Tecnológica (RFEPCT).
Oliveira, Maria Auxiliadora Monteiro   +1 more
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Development education in higher education: Ethnographic research as a development education methodology

open access: yesPolicy and Practice: A Development Education Review, 2006
Roland Tormey and Marie Kiely explore the capacity to use the process of learning to carry out ethnographic research as a vehicle for enabling students to learn, in an active way, the core thinking skills of development education, in higher education.
Roland Tormey, Marie Kiely
doaj  

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