Results 71 to 80 of about 2,263,752 (207)
Investigation of Workload Control Methods for Shops with Re-Entrant Flows
Management Systems in Production EngineeringThe re-entrant flow with an unpredictable nature of arrival would apparently harm production plans and schedules in flow type of shops. The re-entrant flow with varied arrival frequencies in rotor blade manufacturing is quite complicated and results in ...
Prabhu Aruna +3 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Discover Applied SciencesGrowing plastic bottle consumption and insufficient waste management are accelerating the accumulation of floating plastic debris in the UAE seas, which causes degradation of marine ecosystems and threatens sustainability, livelihoods, and essential ...
Bilal Baslar +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Spatial epidemiology of dengue and chikungunya in Karnataka using GIS-based analysis
Global Health ActionBackground Dengue and chikungunya are major vector-borne diseases with significant public health concerns. Understanding their spatial distribution is crucial for effective disease control and prevention strategies.
Prathiksha Prakash Nayak +3 more
doaj +1 more source
Tuning Journal for Higher Education, 2014 Editorial Team Tuning Journal for Higher Education
doaj +4 more sources
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Tuning Journal for Higher Education, 2014 Editorial Team Tuning Journal for Higher Education
doaj +4 more sources