Results 91 to 100 of about 3,003,635 (305)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Evaluation of mean glandular dose in relation to breast density in digital mammography
Background Mammography is considered an ideal tool for breast cancer screening due to its proven effectiveness, which has led to its widespread use as the primary imaging modality for early detection.
Fatemeh Amiri +7 more
doaj +1 more source
Higher Education—Educating for Higher Order Skills
Preparing college students for a knowledge-based economy is a challenge that requires curriculum design that puts more emphasis on learning skills than on content to be taught. Cognitive skills should be practiced in a context of some content, but the choice of content, the choice of the learning environment, and the choice of the assessment procedures
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
This paper describes the potential of carbon dot nanocomposites (CDs) synthesized from waste materials by top-down and bottom-up state-of-the-art approaches.
S. Varadharajan +4 more
doaj +1 more source
Other title: Sharing courses/programs at Ohio's colleges and universities
"September 2017."Background -- Research -- Framework -- Recommended steps to implementing an institutional course/program collaboration -- ConclusionOhio Revised Code Section 3333.90 requires the Ohio Department of Higher Education (ODHE) to establish a ...
Ohio. Department of Higher Education
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We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Diversification of Higher Education
During the 1980s, most European countries underwent substantial changes in their economic and educational systems. During the period it became clear that the discussions were going to be centered around the rapid changes being experienced by the higher ...
UNESCO European Centre for Higher Education
core
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

