Results 61 to 70 of about 22,000,385 (296)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The objective of this design was to conduct an observational study comparing anthropometric characteristics, cognitive functions, as well as gross and fine motor skills.
Mohamed-Amine Ltifi +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Equity Policies in Global Higher Education [PDF]
This book discusses and analyses global policies and practices aimed at promoting equity in higher education participation and attainment. Although the massification of higher education systems has facilitated the participation of students from deprived ...
core +1 more source
Mid-biennial budget adjustments for higher education
Title from PDF cover (viewed July 2, 2007).; At head of title: Highlights.; "April 2006."; Previously published: Operating budget adjustments for higher education / Board of Governors for Higher Education, Department of Higher Education, State of ...
core +1 more source
tool to assess teamwork performance in higher education
Purpose: In this article, we present a tool for assessing the performance of teamwork activities. The results obtained from this tool can be used to guide teamwork learning and mentor students by giving them feedback on their work. Design/methodology/approach: The tool was based on a model of teamwork effectiveness from the literature.
Elisabeth Viles Diez +2 more
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Mid-biennial operating budget adjustments for higher education
Title from PDF cover (viewed July 5, 2007).; At head of title: Highlights.; "March 2004."; Previously published: FY 2003-05 biennial operating budget for higher education / Board of Governors for Higher Education, Department of Higher Education, State of
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

