Results 61 to 70 of about 2,408,302 (295)
Energies, 2017 Waste residues produced by agricultural and forestry industries can generate energy and are regarded as a promising source of sustainable fuels. Pyrolysis, where waste biomass is heated under low-oxygen conditions, has recently attracted attention as a ...
Xing Yang +13 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
AI-based algorithms for estimating hydrochar properties in terms of biomass ultimate analysis
Results in EngineeringHydrochar, a sustainable biofuel derived from biomass via hydrothermal carbonization, requires precise prediction of its yield and higher heating value (HHV) for efficient utilization.
Raouf Hassan +2 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Influence of A Novel Catalysis on The Pyrolysis Yields Obtained by Two Different Reactors
Journal of Advanced Research in Natural and Applied Sciences, 2020 In the present study mixtures of polymeric and cellulosic biomass materials were pyrolized in the presence of two different catalysts (sepiolite and aluminium bauxite) in various ratios by two different reactors; a rotary kiln reac-tor (RKR) and a fixed ...
Mert Kılınçel +2 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Revista Facultad de Ingeniería Universidad de AntioquiaIn Ecuador, extensive coconut (Cocos nucifera) harvesting generates large quantities of waste, including husks, shells, and fibers, posing environmental and economic challenges.
Luis Velázquez-Araque +2 more
doaj +1 more source